Gene Expression
Enzymes
Central Dogma
Translation/Transcription
Pop Culture
100
What causes Genes to be expressed?
Regulatory Proteins
100
Place where substrate binds
Active Site
100
What is the Central Dogma of Molecular Biology?
DNA is transcribed into mRNA which brings the info to the Ribosome to be translated into a protein.
100
Where does Transcription happen?
Nucleus
100
The Rizzler
200
Where do regulatory proteins bind?
Regulatory Sequence
200
Molecule that binds to enzyme to be broken down or built up
Substrate
200
Whate do mRNA, tRNA and rRNA stand for
Messenger Ribonucleic Acid
Transfer Ribonucleic Acid
Ribosomal Ribonucleic Acid
200
Where does translation happen?
Ribosome
200
What is the controversy currently surrounding Hailey Bieber (Justin Bieber's wife)?
She dresses and poses exactly like Justin Bieber's Ex, Selena Gomez, and even copied her tattoo. She also used to be a Justin superfan and stalked him as a teenager
300
What is the portion of DNA that tells a protein how to get made called?
Coding Sequence
300
What causes an enzyme to be non-functional?
A change in shape at the active site.
300
Why do we need RNA to make proteins?
DNA can't leave the nucleus and proteins are made outside the nucleus
300
Transcribe this in under 30 seconds:
A A A A T G T T C G C G C A T A C C G
U U U U A C A A G C G C G U A U G G C
300
Who is Livvy Dunne dating?
Paul Skenes (Pittsburgh Pirates Pitcher)
400
Name 1 way regulatory proteins get signaled to be made?
Hormones, Food, Sunlight, Age, more
400
Give and example where it is bad if an enzyme works too well.
Enzyme (MAO) converting Serotonin to other molecules.
Cell growth enzymes causing cells to grow and dive too much (tumor/cancer)
400
List 5 differences of DNA and RNA.
- RNA has a Uracil base, DNA has Thymine
- RNA has Ribose sugar backbone, DNA has Deoxyribose
- RNA is single stranded, DNA is double stranded
- RNA can leave the nucleus
- RNA has different variations that perform different jobs.
400
Translate this DNA sequence into tRNA in under 30 seconds:
T A T G C T G C C A A T G C T A T T T
U A U G C U C G G A A U C G U A U U U
400
What are the requirements for movie to pass the Bechdel Test?
1. The film must have at least two named female characters
2. These two female characters must have a conversation with each other.
3. The subject of their conversation must be something other than a man. (This means their conversation can be about anything, including other women, work, hobbies, or personal experiences, but it should not be focused on or about a man)
500
Name all 5 Steps for how a protein gets made
1) Regulatory Protein must binds to a Regulatory Sequences so that the DNA coding sequence can be read
2) RNA Polymerase enzyme unwinds DNA and starts making a complimentary mRNA strand
3) Once the mRNA strand is made it will go out to the cytoplasm and to a Ribosome
4) In the Ribosome corresponding tRNA molecules (with correct anti-codon) will attach to the mRNA.
5) The tRNA has an Amino Acid attached to it which will combine with other Amino Acids as the tRNA’s bring them in. The attached Amino Acids form a Protein
500
Explain how an animal becomes albino
Colorless molecules are not given pigment due to a pigment enzyme becoming non-functional.
500
Explain the function of tRNA and how it does its job
tRNA's job is to bring Amino Acids to the Ribosome so it can bind with other Amino Acids and create a Protein. It binds to mRNA by having an Anticodon that is complimentary to the codon of the mRNA its attaching to. Adjacent tRNA's that are attached to mRNA then join their Amino Acids together to make a protein
500
Tell me the Amino Acid Sequence in under 1 minute based off this Sequence of DNA:
T A C G G G C A T A C T C C C T A T
Met Pro Val STOP
500
Name at least 2 French bands/musical artists
Popular answers may be: Daft Punk, Phoenix, Justice, Melody's Echo Chamber, Stereolab