Misfits & Miscellany
This is a mutation that occurs spontaneously in a germ cell.
What is a de novo mutation?
This term, associated with the FBN1 gene, indicates that it will express itself and cause problems.
What is dominant negative?
Chromosomes that match up during meiosis that have similar size are known as this.
What is a homologous pair?
Total and accurate replication of this molecule is necessary to pass the G2 checkpoint.
What is DNA?
This three word definition sums up cancer.
What is uncontrolled cell division?
This blood type can be safely received by all patients.
What is O-?
This is the likelihood that a child will develop Huntington's Disease if one parent is homozygous dominant and the other is homozygous recessive.
What is 100%?
This syndrome can be described as "45, X."
What is Turner syndrome?
This process of cell division requires two rounds of metaphase, anaphase, and telophase.
What is meiosis?
This side of the colon is most often affected by Lynch syndrome.
What is the right side?
This is what we call a mutation that adds a new property or increases gene activity.
What is a gain of function mutation?
Duchenne muscular dystrophy shows this inheritance pattern.
What is X-linked recessive?
This syndrome is caused by trisomy 18.
What is Edward's syndrome?
This is programmed cell death, often due to DNA replication errors.
What is apoptosis?
This protein, a tumor suppressor, is involved in DNA repair.
What is BRCA2?
Klinefelter syndrome is not associated with this effect.
What is the maternal age effect?
A mother who is a carrier for Duchenne muscular dystrophy has this chance of her sons developing the disorder.
What is 50%?
Down syndrome can result from this meiosis error, in which one "greedy" cell takes more genetic information than the other.
What is nondisjunction?
This disorder, common in Africa, provides some resistance to malaria.
What is sickle cell disease?
This is the primary risk factor for developing colorectal cancer.
What is carcinogen exposure?
This notation means the amino acid glycine (G) at amino acid position 542 is replaced by a stop codon.
What is G452X?
This protein is reduced or eliminated in people with hereditary hemochromatosis.
What is hepcidin?
This type of nondisjunction occurs when a chromosome breaks at the centromere and some genetic information attaches to a different chromosome.
What is Robertsonian?
This portion of the cell cycle, between G1 and G2, involves duplicating chromosomes.
What is the S Phase?
This type of melanin is produced by a recessive allele.
What is pheomelanin?