Mitosis and Meiosis
Pedigree
Terminology Review
Transcription and Translation
Mendellian Review
100
What are the stages of mitosis?
Prophase, Metaphase, Anaphase, Telophase
100
What is the mode of inheritance on this pedigree?
This is autosomal dominant
100
What is epistasis?
This is the phenomenon in which one gene controls the outcome of another gene
100
What is the central dogma?
DNA -> mRNA -> Protein
100
what would be the expected genotypic distribution for a monohybrid cross between a heterozygote and homozygote?
1:1
200
What are the three key differences between mitosis and meiosis?
Mitosis is for somatic cells where meiosis is for gametic cells. Meiosis also has two stages, meiosis 1 and 2 where mitosis only has one stage. Meiosis produces haploid cells.
200
What is the mode of inheritance on this pedigree?
This is X-linked Recessive
200
what is a sister chromatid?
Sister chromatid is a term that describes one of two chromatids that create the same chromosome. They are joined together by a common centromere.
200
what RNA molecule is involved in the translation process?
tRNA
200
what is the expected genotypic distribution in a dihybrid cross between two heterozygotes?
9:3:3:1
300
What is happening in metaphase of mitosis?
The chromosomes line up at the metaphase plate due to the action of microtubule spindle fibers.
300
The pedigree below tracks the presence of attached earlobes through a family's generations. Having attached earlobes is an autosomal recessive trait. 
If individual III-6 married a man who was homozygous for unattached earlobes, what is most likely to be true regarding their children?
All of their children will have unattached earlobes.
300
What is co-dominance?
Both alleles of a genotype are expressed which can create a third hybrid phenotype
300
what RNA molecule is involved in the splicing that occurs during transcription?
snRNA
300
what is the law of independent assortment?
genes will assort themselves independently of each other
400
What stage of either mitosis or meiosis 1 or 2 is this?
This is meiosis anaphase 1
400
This tracks Duchenne Muscular Dystrophy
What is the mode of inheritance and what is the percentage chance that the child between Individual II-3 and a carrier woman will have a daughter with DMD?
This is an X-linked recessive disorder and the chance that the child will have the disorder will be 25%
400
What is a histone?
This is a protein that acts in compaction, DNA gets wrapped around histones so that it all can fit inside the nucleus.
400
what is added to an mRNA molecule to prevent its degradation?
5' methylguanosine cap
400
Imagine that there are two genes involved in producing black coat color in rabbits (A and B). At least one dominant allele for each gene is required for black coat color; rabbits that are homozygous recessive for either or both genes are white.Thumper is a white rabbit of genotype aaBB. Mr. Bun is a white rabbit of genotype AAbb.Thumper and Mr. Bun mate and have 10 female offspring, and those females are bred to males of genotype aabb, producing 200 offspring.
what is the phenotype and genotype of the F1 females?
If genes A and B are located on the same chromosome and are 10 map units apart, what will be the distribution of phenotypes among the testcross offspring?
black, AaBb.........(black, Ab//aB)
10 % of the gametes will be recombinant (AB or ab). 90% of the gametes will be Ab or aB. Thus 5% of the offspring will be AaBb Black, and 95% will be white.
500
What stage of either mitosis or meiosis is this?
This is meiosis anaphase 2
500
This pedigree tracks the presence of attached earlobes
What is the mode of inheritance on this pedigree and what would the genotype of individual II-3 be?
500
what is ploidy?
the number of sets of chromosomes in a cell
500
what is the name of the segment of DNA which singals that a gene can be transcribed?
(hint: Transcription factors bind here)
TATA box
500
What are the relevant Bombay locus and ABO locus genotypes of the mother, father, and child in the limerick below, assuming that the couple are actually the parents of the baby?
A lady, type O, from Bombay, Had a baby with blood type A, Her husband, type B, Said how can this be? Explain, or I’ll go away!
Mom hhAA or hhAi; Dad HHBi; Child HhAi