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More Jeers for Beers
Mind your MOA
PK/PD of Aging
Med use in the elderly
Way too many Beers
100
True/false Beers criteria must always be followed.
What is false (guidelines, must use clinical judgement)
100
Main reason to avoid TCAs in elderly
What is anticholinergic effects
100
The PK parameter that has the most effect on drugs in elderly.
What is Excretion/Elimination
100
minimum number of drugs needed to be considered polypharmacy
What is one
100
GI antispasmodics are not recommended primarily due to this side effect.
What is highly anticholinergic
200
Class of antihypertensive agents avoided due to increased risk of orthostasis
What is alpha blockers
200
Enzyme inhibited by galantamine.
What is acetylcholinesterace
200
Metabolic pathway least effected by aging.
What is Phase II metabolism
200
Common resource that lists drugs that are likely to cause problems in elderly.
What is The beers list
200
this drug is not recommended for the prevention of EPS with antipsychotics
What is Benztropine (oral) or Trihexyphenidyl
300
Should avoid this drug class due to increased risk of GI bleeding and fluid retention.
What is NSAIDs
300
This drug "works" by reducing glutamate-mediated exitotoxity
What is Memantine
300
CrCl estimates is (higher/lower) than GFR in elderly
What is higher
300
the omission of drug therapy that is indicated
What is medication underuse
300
This is method is not recommended as a first line of atrial fibrillation in the elderly.
What is rhythm control
400
High doses of this drug for CHF is discouraged due to lack of efficacy and increased toxicity.
What is digoxin
400
The psotoperative medication should be avoided since it can lower seizure threshold.
What is meperidine
400
This is expected with a drug with active metabolytes.
What is have longer half life
400
Failure to fill a prescription is an example of
What is medication non-adherence
400
this hypothyroid medication is not recommended due to concerns of cardiac effects.
What is desiccated thyroid
500
All oral formulations of this medication should be avoided due to carcinogenic potential and lack of cardioprotective effects
What is estrogen
500
The two drug classes that can treat serious/dangerous hyper-sexuality in patients without an underlying mania.
What are antiandrogens, antipsychotics
500
Decreased first pass metabolism will have this effect on enalapril.
What is decrease activation, slowed or reduced efficacy.
500
Where most of the errors occur in adverse drug events (two areas)
What is ordering and monitoring
500
A 300 mg dose of this NSAID would be appropriate in certain patients suffering from acute MI.
What is Aspirin