Hold the Medication
T or F
Lipophilic meds have higher volume of distribution in the elderly patient
What is True
This is routinely checked when ordering antipsychotics in the hospital
What is EKG
A major tenet of prescribing for the elderly: Start low and ___
What is Go slow
Factor(s) considered when adjusting home regimen
What are renal/liver function, perioperative period, drug interactions with new meds, adverse events
Double Jeopardy
These processes together describe pharmacokinetics (Name all 4)
What are Absorption, Distribution, Metabolism, Elimination
Double Jeopardy
This combination medication is used for treating a common geriatric disease state associated with cognitive decline and motor dysfunction. In addition, it can contribute to orthostatic hypotension.
What is Carbidopa/levodopa
These are usual classes of medications associated with adverse drug events
What are anticoagulants, hypoglycemics, analgesics
The use of Alpha 1 blockers should be avoided in the geriatric population due to the risk of this.
What is orthostatic hypotension?
These medications should be avoided in your crazy, itchy patients over the age of 65.
What are first generation antihistamines? Highly anticholinergic - risk of confusion, dry mouth, constipation
Study of how the body responds to drugs
What is Pharmacodynamics
Double Jeopardy
This is the new way of monitoring Vancomycin therapy in our hospital
What is AUC (area under the curve)
List 3 medication classes in the elderly population that predisposes them to falls.
What are anticholinergic, psychotropic, and cardiovascular medications
This ADR is associated with a commonly-prescribed medication that reduces ASCVD risk is (arguably) more common in geriatric patients and rarely, if very severe, can be achy
What are statin-induced myopathy, rhabdomyolysis
Double Jeopardy
This cardiac drug has a narrow therapeutic index, has a specific toxicity syndrome, is eliminated renally, and has several documented drug-drug interactions. Geriatric patients can occasionally exhibit s/s of toxicity even at therapeutic levels.
What is digoxin?
Study of how drugs change in the body
What is Pharmacokinetics
True or False
All benzodiazepines should be withdrawn gradually if taken for more than 4 weeks as there is a risk of causing a benzodiazepine withdrawal syndrome if stopped abruptly
True
Double Jeopardy
This is the inappropriate use of medication B to combat side effects of medication A which are misinterpreted as a new medical condition
What is Prescriber cascade
Double Jeopardy
Orthostatic hypotension is a term used to describe these effects - Systolic change of ___ or Diastolic change of ____ or signs/symptoms (name 1 _____ related to ______. Must get ALL 4 for points.
20mmHg,
10mmHg,
dizziness, syncope, blurry vision, confusion, nausea,
change in position
Thiazides and SSRI's are much more likely to cause this abnormality in the geriatric population.
What is hyponatremia?
In elderly patients with muscle mass reduced beyond normal aging, the Cockroft-Gault equation _____ CrCl
What is overestimate
True or False
PPI for uncomplicated peptic ulcer disease should be used for 12 weeks
False
8 weeks. Prolonged use associated with fractures, cognitive changes
This is a very serious adverse event that mulitidisciplinary teams are often seeking to eliminate. Better watch out for hypoglycemia, hypotension, dizziness
What is fall or acute cognitive decline
3 risk factors for adverse drug events in geriatrics patients
What are Polypharmacy, Adherence, Altered physiology