Know Thy truFreeze LN2
Name that Ablation
Deep Freeze Science
Ice, Ice, Necrosis
Tank You Very Much
100

The extremely low temperature where nitrogen gas turns to a liquid state

What is -196 degrees Celsius?

100

List an alternative type of cryogen available in GI.

What is Nitrous Oxide or N2O?

100

This makes up 70-80% of total cell volume.

What is water

100

Necrosis is another word for this.

What is cell death?

100

The name of a double-walled tank that holds Liquid Nitrogen at hospitals.

What is a dewar tank?

200

This makes up 78% of the earth’s atmosphere – it’s an odorless, colorless, non-toxic, & non-flammable gas.

What is nitrogen?

200

This type of cryogen is cleared by the FDA to treat ONLY Barrett’s with dysplasia and GAVE.

What is N2O used by C2 Balloon.

200

This provides cellular support for cells and is sometime referred to as the ECM.

What is the extracellular matrix?

200

This forms inside and outside of cells when they are exposed to cryo.

What are ice crystals?

200

The size of the LN2 dewar tank in the truFreeze console.

What is 15 Liters? Fills to 13.7 Liters.

300

Name 3 contraindications for using truFreeze LN2 in the GI Tract.

What is Pregnancy, Mucosal Breaks, Restricted Lumen preventing CDT or gas venting & Food in the stomach?

300

Name a type of ablation commonly used in GI that causes a layer of eschar (scarring).

What is RFA or Argon?

300

The key benefit of repeated freeze/thaw cycles with cryotherapy.

What is more cellular or tissue destruction or greater kill zone?

300

True or False: LN2 Cryotherapy induces tissue necrosis or cell death through controlled freezing and thawing cycles.

What is true?

300

Console LN2 Tank works most efficiently at this level of fill or above.

What is 50%?

400

Name the 4 medical professionals needed in the room to support a truFreeze procedure.

Who is the 1)Physician, 2)Anesthesia/CRNA, 3)Belly Monitor, and 4)Console Operator?

400

True or False: With heat ablation, more energy results in deeper treatment beyond the scar.

What is false?

400

Malignant cells have less water, are more vascular, and produce a higher rate of______.

What is heat?

400

The only cryogen in GI that gets cold enough to overcome body temperature to cause necrosis in malignant cells.

What is Liquid Nitrogen?

400

The PSI required on an LN2 source tank to fill a truFreeze console.

What is 22 PSI?

500

The liquid-to-gas expansion ratio of nitrogen.

What is 1:700?

500

This ablation technology consistently treats to .7mm or 700 microns and is measured in joules.

What is RFA?

500

Name the 1 zone formed in ablated tissue with cryothermic (cold) energy?

What are the complete ablation zone ot transition zone?

500

The temperature required to cause malignant cell death.

What is -50 degrees Celsius?

500

The number of procedures that can be complete with a tank level indictor of yellow?

What is at least one procedure?