Laxatives
This should be monitored due to the potential for fluid and electrolyte imbalances with laxatives.
What is electrolyte balance (especially potassium and chloride)?
These agents are used to enhance gastric motility and treat conditions like GERD and diabetic gastroparesis.
What are prokinetic agents?
This agent is used for healing gastric or duodenal ulcers not caused by NSAID use.
What is Sucralfate?
Bismuth subsalicylate should be avoided in this age group due to the risk of Reye’s syndrome.
What are children under 3 years old?
This is the goal of tapering a patient off a PPI.
What is to reduce dependence while managing symptoms?
These two H2 blockers are approved for use in children.
What are ranitidine and famotidine?
This class is the best choice for rapid relief from constipation.
What are stimulant laxatives (or osmotic like magnesium hydroxide)?
This is the only FDA-approved prokinetic agent in the U.S.
What is metoclopramide (Reglan)?
This is the preferred first step in managing NSAID-induced gastric ulcers.
What is discontinuing NSAID therapy?
Antacids are not the first-line treatment for this condition when H. pylori is present.
What is peptic ulcer disease?
These two PPIs are approved for use in children.
What are pantoprazole and omeprazole?
What effect does smoking have on H2 blocker absorption?
What is it decreases absorption?
For long-term constipation management, this class is considered safest.
What are bulk-forming laxatives?
This is the most serious Black Box Warning associated with long-term metoclopramide use.
What is tardive dyskinesia?
Sucralfate promotes ulcer healing by forming this over ulcer tissue.
What is a protective barrier?
Excessive use of opioid anti-diarrheals may cause this life-threatening colonic complication.
What is toxic megacolon?
PPIs should not be used long-term without monitoring because they can mask this serious condition.
What is gastric cancer?
This H2 blocker is 30 to 60 times more potent than cimetidine.
What is famotidine?
Bulk-forming laxatives are safest for this population.
What are pregnant women?
Prokinetic agents are contraindicated in patients with These conditions
What is GI hemorrhage, mechanical obstruction or perforation?
This is the reason Sucralfate should be taken on an empty stomach.
What is to allow better binding to ulcer tissue?
This drug used for IBS-D has a black box warning for severe constipation.
What is alosetron?
Prolonged PPI use can lead to this skeletal complication.
What is osteoporosis or increased fracture risk?
This H2 blocker is associated with hepatocellular injury.
What is nizatidine?
This class of laxatives carries no risk for dependence or electrolyte imbalance but can be expensive.
What are chloride channel activators?
These two infections-related drugs have off-label prokinetic properties.
What are erythromycin and azithromycin?
Misoprostol is contraindicated in
What is pregnancy?
This combination of three drugs is the first-line treatment for PUD caused by H. pylori.
What are a PPI + clarithromycin + amoxicillin?
Long-term PPI use may result in deficiencies of these three nutrients.
What are iron, vitamin B12, and calcium?
This side effect may occur in men taking cimetidine, due to antiandrogenic activity.
What is gynecomastia or impotence?