GI Jeopardy

Anatomy & Embryology

100

Passing through the epiploic foramen will take you into this space that sits behind the stomach

Omental Bursa (lesser sac)

200

McBurney's point is the surface marking for the appendix. Where is it?

2/3 of the way from the umbilicus to the right ASIS

300

What is the double layer of peritoneum that suspends the small intestine from the posterior wall, carrying its blood vessels, lymphatics and nerves?

Mesentery

400

What 2 parts of the colon have their own mesocolon and are fully intraperitoneal? 

Transverse and sigmoid colon

500

The ventral mesentery is derived from what structure?

Septum Transversum

Upper GI Pathology and Pharm

100

What cell secretes HCl and intrinsic factor for B12 absorption?

Parietal cell

200

Gastrin from G cells stimulates acid indirectly by causing which cell to release histamine?

Enterochromaffin-like cell

300

In Barrett's oesophagus, what is the change in epithelium? What cancer type does this raise the risk of?

Non-keratinised stratified squamous -> simple columnar.

Adenocarcinoma

400

What percentage of H.pylori infections will lead to the devlopment of gastric cancer?

1-3%

500

What class of drugs create a mechanical barrier that suppresses the gastric reflux at the lower oesophageal sphincter?

Alginate-antacid combination (Alginates)

Gut Pathogens

100

What organism causes "rice-water" stools?

Vibrio Chloerae

200

Traveller’s diarrhoea from ETEC is what type of diarrhoea? Why?

Secretory - active electrolyte secretion into the lumen

300

Campylobacter infection can cause what syndrome 10-14 days after infection?

Guillain-Barre Syndrome

400

What gram-positive anaerobic bacteria spores survive with improper refrigeration causing toxins in the food?

Clostridium perfringens

500

What is the complication of Shiga toxin-producing E. coli (STEC) that occurs in 5% of cases?

Haemolytic Uraemic Syndrome (= Acute renal failure)

GI Physiology & Pharm

100

What hormone released from duodenal M cells stimulates the migrating motor complex during fasting?

Motilin

200

What pacemaker cells spontaneously depolarise but never reach the threshold alone?

Interstitial cells of Cajal

300

Loperamide binds to which receptors in the myenteric plexus to reduce the release of which neurotransmitter?

Mu-opioid receptors, acetylcholine

400

What muscle relaxes, straightening the anorectal angle to allow voluntary defecation?

Puborectalis muscle

500

Targin treats opioid-induced constipation by pairing oxycodone with which antagonist?

Naloxone