GI Pharm!

Constipation

100

First line of treatment for chronic constipation

bulk-forming laxative

200

Glycerin is commonly used as a laxative in this patient population

Pediatric

300

These are diphenylmethane derivative stimulant laxatives

Dulcolax and Senekot

400

Common side effects of stimulatory laxatives

abdominal cramping, hypokalemia, hypernatremia

500

Lactulose is this type of laxative; it is also used to treat this condition

synthetic disaccharide hyper osmotic agent; hepatic encephalopathy

IBD

100

First line of treatment for mild IBD

aminosalicylates

200

Aminosalicylates are taken PO but considered _____ due to _______

topical medication; low systemic absorption

300

The difference between 6-Mercaptopurine and Azathioprine

Azathioprine is a prodrug which is rapidly converted to 6-Marcaptopurine

400

These are examples of anti-interleukin therapy (brand names)

Skyrizi, Stelara, Omvoh

500

Cyclosporine is a(n) ______ which is indicated in ________

immunosuppressant; fulminant ulcerative colitis

Diarrhea + IBS

100

The absolute most important treatment for diarrhea is

rehydration

200

first line treatment for diarrhea

loperamide (Imodium)

300

Antispasmodic medications include

Bentyl and Levsin

400

Lomotil is a combination of _____ and _____ and is primarily used in ________

opioid and anticholinergics; chemotherapy

500

This class of antidepressants is effective for IBS patients separately from mood effects. Examples include

Tricyclics; Amitriptyline and Nortriptyline

Nausea/Vomiting

100

Antihistamines and anticholinergics are effective against this type of nausea, because they block these type of receptors

vestibular; H1 and muscarinic

200

MOA of phenothiazines

antidopaminergic in the CTZ

300

These two anti-nausea medications work on the GI tract

aprepitant and metroclopramide

400

To block the cerebral cortex pathway for nausea, these two medications can be given

Xanax and Ativan

500

Dexamethasone is only given for nausea in combination with

5-HT inhibitor and NK receptor antagonist

GERD/PUD

100

Important drug interactions of antacids

chelation of certain antibiotics

200

The difference in action site between PPIs and PCABs

PCABs concentrate inside the parietal cell, while PPIs act on the outside

300

The only H2RA with a significant side effect profile is _____. These side effects include ______ in women and _______ in men

Cimetidine; galactorrhea; gynecomastia

400

Triple therapy for H/ Pylori includes

vonozapram, amoxicillin, and clarythromycin

500

Sydney takes approximately ____ Tums per day

4