Mechanism Matters
This medication blocks the final step of gastric acid production.
What is a PPI (omeprazole)?
A patient taking ondansetron should be monitored for this cardiac complication.
What is QT prolongation?
First-line mild therapy for ulcerative colitis.
What is 5-ASA (mesalamine)?
Before starting infliximab, patients must be screened for this infection.
What is tuberculosis?
A patient on infliximab presents with cough and fever. The priority action is to:
Hold medication and notify provider.
Select all medications that suppress immune function:
A. Prednisone
B. Infliximab
C. Azathioprine
D. Ondansetron
E. Mesalamine
Answer: A, B, C
This drug activates chloride channels to increase intestinal fluid secretion.
What is lubiprostone?
This medication is contraindicated in pregnancy because it can stimulate uterine contractions.
What is misoprostol?
This medication is used for IBS-D and works locally in the intestine as an antibiotic.
What is rifaximin?
Azathioprine therapy requires monitoring of this blood component.
What is white blood cell count (CBC)?
A patient taking sucralfate should take it on an empty __________.
What is stomach?
Select all anticholinergic side effects of Bentyl:
A. Dry mouth
B. Urinary retention
C. Bradycardia
D. Blurred vision
E. Diarrhea
A, B, D
This medication blocks 5-HT3 receptors to prevent nausea and vomiting.
What is ondansetron?
This medication should be held if a patient develops fever and signs of infection.
What is infliximab? (Also acceptable: azathioprine)
This medication reduces abdominal cramping in IBS.
What is dicycloverine (Bentyl)?
Long-term PPI therapy may lead to deficiency of this vitamin.
What is vitamin B12?
A patient with GERD reports minimal relief from antacids. The next stronger class is:
What is an H2 blocker or PPI?
Select all drugs used to treat ulcerative colitis:
A. Mesalamine
B. Infliximab
C. Lubiprostone
D. Azathioprine
E. Rifaximin
A, B, D
This biologic works by inhibiting TNF-alpha.
What is infliximab?
A patient with urinary retention should avoid this anticholinergic drug.
What is dicycloverine (Bentyl)?
This drug is used for chronic constipation by stimulating 5-HT4 receptors.
What is a 5-HT4 agonist?
Corticosteroid therapy may increase this lab value.
What is blood glucose?
A Crohn’s patient on prednisone for 6 months is at risk for this bone complication.
What is osteoporosis?
Select all long-term risks of corticosteroids:
A. Hyperglycemia
B. Osteoporosis
C. Immunosuppression
D. QT prolongation
E. Hypertension
A, B, C, E
This immunomodulator suppresses purine synthesis to decrease lymphocyte production.
What is azathioprine?
This anti-diarrheal should NOT be given to a patient with bloody diarrhea and fever.
What is loperamide?
Stress ulcer prophylaxis in hospitalized patients often includes this drug class.
What is a PPI?
A WBC of 3.0 in a patient taking azathioprine indicates this complication.
What is bone marrow suppression / leukopenia?
A patient with IBS-D develops fever and abdominal tenderness. The nurse should avoid giving:
What is loperamide?
Select all medications used for nausea and vomiting:
A. Ondansetron
B. Scopolamine
C. Aprepitant
D. Mesalamine
E. Loperamide
A, B, C