Hepatology 1
Diagnostic testing for chronic hepatitis C
HCV antibody followed by HCV RNA
Diagnosis suggested by elevated alkaline phosphatase and positive antimitochondrial antibody
PBC
Most common cause of abnormal liver test results
MASLD
First step in managing uncomplicated GERD
Empiric PPI
Celiac disease treatment
Lifelong avoidance of wheat, rye, and barley
USPSTF hepatitis C screening indication
All patients age 18-79 years
Initial treatment for PBC
Ursodeoxycholic acid
Treatment for SBP
Third-generation cephalosporin plus albumin
Diagnosis suggested by dysphagia to solids alone
Mechanical obstruction
Laboratory test that may help distinguish IBD from IBS
Elevated fecal calprotectin
Diagnosis suggested by normal ALT/AST, positive HBsAg, positive HBeAg, high HBV DNA
Hepatitis B infection immune-tolerant phase
Diagnosis suggested by RUQ pain without gallstones on ultrasound in critically ill patient
Acalculous cholecystitis
Diagnosis suggested by pruritus and total bile acid level >10 μmol/L in the second- or third-trimester of pregnancy
Intrahepatic cholestasis of pregnancy
Gold standard diagnostic test for achalasia
Esophageal manometry
Crohn disease colonoscopy finding
Mucosal inflammation with skip areas
Hepatitis B treatment indications
ALF, immune-active phase, cirrhosis, pregnant patients with viral load >200,000 IU/mL in third trimester
Cholecystectomy indications for asymptomatic gallstones
Gallstones >3 cm, porcelain gallbladder, gallbladder polyp >1 cm
Recommended hepatitis C pretreatment assessment
Cirrhosis assessment with serologic biomarkers and/or elastography
Endoscopic findings in eosinophilic esophagitis
Rings and furrows, luminal narrowing, edema, exudates
Role of systemic glucocorticoids in IBD
Induction of remission, not maintenance therapy
Hepatitis B–associated vasculitides
Polyarteritis nodosa, cryoglobulinemia
PSC gold standard treatment
Liver transplantation
Most common causes of drug-induced liver injury
Acetaminophen, amoxicillin-clavulanate, phenytoin, valproate
Treatment for Barrett esophagus with dysplasia
Endoscopic mucosal resection, followed by radiofrequency ablation or cryotherapy
Test required before thiopurine use
TPMT genotype or phenotype assay