Malkawi's A to Z Pharmacy
Khair's Day Care
Happy Harpole Elementary
Jack's Plumbing Co.
Templeton's Tube Shack
100
What beta blocker drop is beta-1 cardioselective?
Betaxolol
100
What is the gene known to be associated with this?
PAX6
100
What effect does general anesthesia have on IOP in kids? What anesthetic is an exception?
Lowers (except Ketamine, which raises IOP)
100
What is the treatment for congenital glaucoma with a very cloudy cornea? Clear cornea?
Trabeculotomy (cloudy)
Goniotomy (clear)
100
Name a valved and non-valved tube shunt
Valved: Ahmed
Non-valved: Baerveldt, Molteno
200
Which topical glaucoma medication has a Class “c” rating and is therefore considered the safest to use during pregnancy?
Alpha agonists
200
What 2 genes are JOAG associated with?
TIGR and MYOC
200
What age range of congenital glaucoma diagnosis gives the best prognosis?
3-12 months (responds best to angle surgery)
200
75 yoM POM#3 Trab with patent surgical PI. c/o eye pain for 2 days. 1+conj injection, IOP 4, AC 1+ cell. Seidel positive. What is the likely diagnosis? What’s treatment?
Blebitis
Culture and fortified antibiotics
200
What are 3 complications of cyclodestructive procedures?
Hypotony, suprachoroidal hemorrhage, inflammation, CME, RD, phthisis, sympathetic ophthalmia
300
Which class of glaucoma medications should you theoretically avoid in patients with corneal edema?
Carbonic anhydrase inhibitors
300
Name the most common gene associated with congenital glaucoma, and it's inheritance pattern
CYP1B1 (AR)
300
This syndrome can cause glaucoma, retardation, and a deadly nephroblastoma
WAGR Syndrome
300
What were the main findings of the EAGLE study?
In angle closure patients, lensectomy had lower IOP and fewer meds than LPI+meds
300
What post-operative complication causes segmental K edema and obstructs TM outflow, and whitens with argon laser application?
Epithelial ingrowth
400
What is a color-related side effect of prostaglandin analogues? What cell or cellular component is affected, specifically?
Skin/iris hyperpigmentation
Increased melanosomes (not melanocytes)
400
What’s the diagnosis? What’s the inheritance pattern? 
Axenfeld-Rieger (AD)
400
What class of surgery should not be attempted in aniridia patients?
Angle surgery (angle closure)
400
What was the LiGHT trial, and what did it find?
SLT vs meds as initial treatment
IOP control similar, but SLT more cost-effective
400
Advantage and disadvantage of using 5-FU/MMC in trabeculectomy?
Adv: antifibrotic, more success
Disadv: bleb leak, infection, hypotony
500
Describe the IOP-lowering mechanism of PGAs, BBs, AA, CAIs, miotics, and RhoK inhibitors
PGA: increase uveoscleral outflow
BB: decrease aqueous humor
AA: decrease aqueous humor
CAI: decrease aqueous humor
Miotics: increase trabecular outflow
RhoK inhibitors: increase trabecular outflow, decrease episcleral venous pressure
500
What are the numerical criteria for corneal diameter in pediatric glaucoma? (3 criteria)
>11 mm at birth
>12 mm at 12 months
>13 mm after
500
Give the range of normal values for corneal diameter in a newborn, 2yo, and adult
Newborn: 9.5-10.5 mm
2yo: 11-12 mm
Adults: 11-12 mm
500
What is meant by "hypertensive phase" after tube surgery, when does it happen, and what causes it?
Sudden IOP elevation 3 weeks - 3 months after tube surgery. Fibrotic capsule around plate becomes less permeable
500
In the Tube vs Trabeculectomy (TVT) study: what were the treatment groups? What were the main results?
(Trab + MMC) vs Baerveldt
Trab: HIGHER failure rate, HIGHER reoperations, EQUAL IOP control/#of meds