Pharmacokinetics of glyburide
Understanding glyburide
Patient Considerations/teachings
100
What is the most common adverse reaction of Glyburide?

Hypoglycemia

100

what is the most common way to induce glyburide

orally

100

is glyburide dangerous to children

yes

200

Where is glyburide primarily metabolized?

In the liver

200

What effect does glyburide have

lowers blood glucose levels

200

What should patients carry along with them if they are taking glyburide

sugar

300
What is the half-life of glyburide

10 hours

300

What is a similar medication to glyburide?

Glipizide or glimepiride

300

What can glyburide also treat?

gestational diabetes

400

What can renal issues cause Glyburide to do?

Renal issues may cause drug accumulation and prolonger hypoglycaemia

400

How does glyburide work

  • Stimulates pancreatic beta cells
  • Binds to sulfonylurea receptors
  • Closes ATP-sensitive potassium channels
  • Cell depolarization occurs
  • Calcium influx triggers insulin release
400

what risk does glyburide have the effects

hypoglycemia risk which can cause falls, confusion, weakness

500

What drugs can displace glyburide

highly protein-bound drugs

500

What therapeutic class does glyburide belong in

oral hypoglycaemic, antidiabetic medication

500

If the patient forgets to take the medication what should they do?

take it right away, or if its close to the next time take it then