Topic 12
The organelle that synthesizes non-secreted proteins.
What is a free ribosome?
This barrier contains two membranes, the inner nuclear membrane and the outer nuclear membrane and is found in Eukaryotic cells.
What is the nuclear envelope?
A type of coated vesicle comprised of units of triskelions.
What is clathrin?
This is an example of a biomolecular condensate responsible for ribosome assembly.
What is the nucleouls?
Proteins recruited by scaffold molecules in a biomolecular condensate.
What are clients?
A low amount of this ion during nuclear import is found in a resting T cell.
What is Ca2+?
A type of signal that returns proteins to the organelle from which they originated.
What are retrieval signals?
The protein responsible for making the final cut of a vesicle from the plasma membrane.
What is dynamin?
Its role is to target a specific protein signal and bind the ribosome, mRNA, and growing peptide to the ER membrane.
What is Signal Recognition Particle (SRP)?
This type of reaction removes hydrogen atoms from organic substrates and are conducted in the organelle known as the peroxisome.
What is an oxidase reaction?
The face of the Golgi apparatus that is furthest from the ER.
What is the trans side of the Golgi apparatus?
A family of enzymes that detoxifies lipid-soluble drugs and other harmful metabolic compounds.
What is the P450 family of enzymes?
A transmembrane protein within the cytosol with a single transmembrane domain close to the C-terminus.
What is tail anchored protein?
This protein translocator is responsible for inserting synthesized proteins that are in the matrix into the inner membrane of the nuclear envelope.
What is the OXA Complex?
These proteins have the ability to change the identity of an organelle based on their role in mediating vesicle traffic and binding.
What are Rab proteins?
The enzyme that organizes disulfide bonds in proteins destined for the intermembrane space.
What is Mia40?
An ER resident protein that adds an additional glucose to unfolded oligosaccharides to maintain an affinity for calnexin and calreticulin.
what is glucosyltransferase (GTF)?
This lipid that is composed of fatty acids and sphingosine, is a precursor at the Golgi apparatus for sphingomyelin and glycosphingolipids.
What is Ceramide?
An enzyme bound by lysosomal hydrolase that transfers a phosphate group that serves as a tag for direction to the lysosome.
What is GlcNAc phosphotransferase?
The proteins responsible for mediating the invagination of the membrane for internalization.
What are ESCRT proteins?