Risk Factors
Therapy Options
Risk/ Coverage
Therapy
Also...Therapy
100
You can alter these types of risks.
What is: Modifiable risk factors
100
If cultures are returned positive, this is the next step.
What is: Adjust ABx therapy
100
Besides MRSA, this bacteria another COMMON pathogen that we DOUBLE COVER empirically.
What is: Pseudomonas
100
This Cephalosporin can be used for EARLY HAP and does NOT need to be renally adjusted
What is: Ceftriaxone
100
These 2 antibiotics are available for MRSA coverage
What is: Vancomycin and Linezolid
200
A GI bleed would need this risk factor as treatment.
What is: Stress Bleeding Prophylaxis (Protonix)
200
If cultures are positive and there IS improvement this is the next step
What is: De-escalation and treatment for 7-8 days.
200
Home infusions and residing in a nursing home are risks for this type of pneumonia
What is: Health care associated
200
DAILY DOUBLE!
What is: See Austin's Answer
200
This is the empiric dose for ZOSYN
What is: 4.5g Q6h
300
Early HAP is defined as this.
What is: Symptoms of pneumonia within 4 days of admission.
300
This is one of the MDR pathogens
What is: MRSA
300
Antibiotic use is associated with these 2 types of risks
What is: MDR and HCAP
300
Create an EARLY onset HAP regimen for Strep. Pneumo
What is: Ceftriaxone OR rFQ OR Unasyn OR Ertapenem
300
Non-responders can be due to what 3 main topics?
What is: Wrong Organism, Wrong Diagnosis, Complications of disease (points for 1, bonus for > 1)
400
Late HAP is defined as this.
What is: Onset of symptoms > 5 days after admission.
400
This is when it's time to initiate broad spectrum antibiotic therapy.
What is: MDR risk factors and Late onset
400
Name 5 risks associated with MDR or HCAP
What is: Look at risk factors
400
What is the MINIMUM duration of therapy for HAP?
What is: 7 days (IDSA page 406)
400
These drugs do NOT need to be renally adjusted. (3)
What is: Ceftriaxone, Moxifloxacin, Linezolid
500
The risk factors are apparent, and HAP/VAP/HCAP is suspected. This is the next step in diagnosis. How long until you recheck?
What is: Obtain LRT sample, recheck in 2 and 3 days.
500
This type of therapy is used if there are NO MDR risk factors and symptoms are present after 48 hours of inpatient care.
What is: Limited spectrum antibiotic therapy
500
How many TOTAL drugs are possible when starting EMPIRIC LATE HAP therapy
What is: 3
500
These 5 antpseudomonal classes are used in empiric therapy for late HAP
What is: Cephalosporin, carbapenem, B-lactam/B-lactamase, rFQ, aminoglycoside
500
Your patient is being EMPIRICALLY treated for LATE HAP. Design a therapy regimen if their renal function is CrCl= 25 mL/min. (Use lexicomp)
What is:Double Check with Austin