Holiday Hazards
Brrrr
Don’t put that in your mouth
Achhoo
Trial (and error)?
100

50/M comes with sudden onset chest pain after forceful vomiting during holiday feasts. This is the best diagnostic test for a life threatening condition.

CT chest with oral contrast.

100

First-line rewarming strategy for mild hypothermia.

What is passive external rewarming?

100

Reheating leftover risotto causes this bug to wreck havoc in your gut.

Bacillus cereus

100

This isolation precaution is recommended in hospitalized patients with Influenza.

Is it droplet?

100

This trial demonstrated mortality benefit from low tidal volume ventilation in ARDS.

Is it ARDS-NET?

200

Classic holiday poisoning from homemade alcohol or windshield washer fluid.

Methanol poisoning

200

This ECG finding is associated with hypothermia.

What are Osborn (J) waves?

200

Soft cheese associated gastroenteritis with placental transmission is caused by this bug

Listeria monocytogenes

200

This is the most common cause of post-Influenza pneumonia.

Is it Staph aureus (accept MRSA)?

200

This trail demonstrated benefit of an SGLT2 inhibitor in HFrEF patients regardless of Diabetes status.

Is it DAPA-HF?

300

A 52/M had fun during the holidays, he binge drank and now has palpitations. This is the most likely diagnosis.

Holiday Heart Syndrome

300

This method best measures core temperature in hypothermia.

Esophageal probe?

300

45/F previously healthy, came to ED after eating home-canned peaches with a pie, her cousins are also presenting with similar symptoms of nausea, vomiting. One day later they started complaining of blurred vision, difficulty swallowing and dry mouth; you also find symmetric descending flaccid paralysis and dilated poorly reactive pupils. In addition to ICU care, administration of this will tremendously help the patient. 

Is it Trivalent Equine Antitoxin? (Accept antitoxin)

300

The active form of oseltamivir inhibits this.

Is it neuraminidase?

300

This trial demonstrated mortality benefit in severe community-acquired pneumonia being treated in the ICU, those who received hydrocortisone.

Is it CAPE COD?

400

Being enclosed within unventilated space with heaters and generators puts you at risk of developing a toxicity which causes inhibition of this enzyme. 

Cytochrome c oxidase 

400

Below this core temperature repeat defibrillation attempts are typically limited if VF or VT is refractory.

<30 degrees celsius

400

32/F with history of asthma presented with acute onset  facial flushing, urticaria and dyspnea approx 20 min after eating tuna sandwich at a deli. She is here with her husband who has similar symptoms but much milder. They most likely have-

Is it Scombroid poisoning?

400

A child with Flu is treated with aspirin and later develops vomiting, confusion and elevated ammonia. The most likely diagnosis is-

Reye Syndrome

400

This trial established early prone positioning as mortality reducing in severe ARDS.

Is it PROSEVA trial?

500

Severe vomiting, sudden onset chest pain and cervical subcutaneous emphysema constitute this triad.

Mackler’s Triad

500

This drug class’ effect is most exaggerated in hypothermia

Paralytics or neuromuscular blockers?

500

23/M went on a holiday trek with his friends, they found these pretty wild mushrooms and after 2 days they are all jaundiced and confused.

Is it Amanita phalloides? (Accept Amanita)

500

The Influenza A virus binds to respiratory epithelial cells through its ____ protein.

Is it hemagglutinin?

500

This trial demonstrated that among hospitalized patients with bloodstream infection, antibiotic treatment for 7 days was noninferior to treatment for 14 days. 

Is it BALANCE trial?