All About the skin
Homeostasis phase
Inflammation stage
Proliferation stage
Remodeling stage
100

Largest organ in the body?

Skin

100

First stage of wound healing?

Hemostasis

100

What color change signals inflammation? 

redness 
100

When does the proliferation stage begin? 

2-3 days after injury

100

Last stage of healing?

Remodeling(Maturation)

200

Outer protective layer of the skin?

Epidermis

200

What happens to blood vessels to reduce bleeding?

Vasoconstriction 

200

Main immune cells that "eat/consume" pathogens? 

Macrophages

200

Cells that move in to build new tissue are called..

Fibroblasts

200

How long can remodeling take?

Over a year

300

Main cells in the epidermis?

Keratinocytes 

300

What forms to seal the wound and block pathogens?

Blood clot

300

Why is inflammation important? 

Kills pathogens and removes debris 

300

Fibroblasts deposit what protein? 

Collagen

300

What is the range by how much function can healed skin recover to its original self? 

50-80%

400

Middle skin layer containing blood vessels, glands, nerves?

Dermis

400

Why is hemostasis critical?

Stops bleeding & prevents infection 

400

Process macrophages use to get rid of bacteria?(consuming debris, dead cells, and pathogens)

Phagocytosis

400

What replaces fibrin during proliferation? 

Connective Tissue (Collagen)

400

Why is scarring common?

Skin does not fully recover at times

500

Protein that makes skin tough and protective?

Keratin 

500

Protein forming cross-links to seal the wound? 

Fibrin
500

What happens to blood vessels during inflammation (opposite of vasoconstriction)?

Vasodilation

500

What do epidermal cells do during proliferation?

Divide to reform skin

500

One mystery about wound healing in humans? 

Origin of fibroblasts or why animals like deer heal better.