Mechanism of Action
GDMT Basics
Miscellaneous
100

This medication class works by acting on the sympathetic nervous system

What are beta blockers?

100

This medication regimen is the gold standard of evidence-based therapies to treat patients with heart failure

What is guideline directed medical therapy (GDMT)?

100

This medication class is widely utilized for symptomatic relief, but has no mortality benefit in patients with heart failure

What are diuretics?

200

This medication class works by blocking receptors that aldosterone binds to

What are mineralcorticoid receptor antagonists? (MRA)

200

Penn Medicine resource for guidelines on medical management of patients with heart failure

What is Penn Pathways?

200

This heart failure classification system uses functional ability to differentiate severity of heart failure

What is New York Heart Association classification?

300

This medication class provides symptom relief by decreasing sodium reabsorption at the loop of Henle

What are loop diuretics?

300

Hormonal pathway in the body responsible for homeostatic control of blood pressure

Renin Angiotensin Aldosterone system (RAAS)

300

This cause of heart failure could be treated with revascularization such as PCI or CABG

What is ischemia?

400

These medications have mechanisms that aren't totally understood, but thought to help heart failure by reducing oxidative stress and metabolic demand

What are SGLT2-inhibitors?

400

These beta blockers act only on the cardiac tissues (i.e. is cardio-selective)

What is:

Metoprolol

Carvedilol

Bisoprolol

Atenolol

Esmolol 

400

This idea refers to the force against which the heart has to pump

What is afterload?

500

This medication class works by increasing the force with which the heart contracts

What are inotropes?
500

This medication class can be utilized when ACEs, ARBs, or ANRIs are unable to be used

What are vasodilators?

500

This idea refers to the amount of blood in the ventricles at the end of diastole

What is preload?