What Am I?
Anemia's
Bleeding Disorders
Heme Disorders
Sickle Cell Disease
100

A client reports glossitis + numbness/tingling. Hgb low, MCV high. This anemia is most likely.

What is vitamin B12 deficiency (pernicious) anemia?

100

A classic “first clue” symptom of iron deficiency anemia that NCLEX loves is craving this nonfood item.

What is ice (pagophagia) / pica?

100

Deep bleeding and hemarthrosis strongly point to this inherited disorder.

What is Hemophilia A?

100

In DIC, this lab is elevated due to increased clot breakdown.

What is D-dimer?

100

List 6 common triggers for a sickle cell crisis. 

Dehydration, Hypoxia, Infection, Cold Exposure, Stress, Strenuous Exercise, Surgery, Pregnancy
200

I am the transfusion reaction with sudden respiratory distress + pulmonary infiltrates that occurs within hours of transfusion and is NOT improved by diuretics.

What is TRALI (transfusion-related acute lung injury)?

200

List 3 priority nursing actions before initiating a blood transfusion?

What is verify informed consent and type & crossmatch/compatibility and obtain baseline VS?

200

Hemophilia bleeding is commonly deep tissue/joint bleeding. The correct non-pharmacological nursing care is:

What is RICE?

Rest, Ice, Compression, Elevation

200

Describe the pathophysiology behind DIC.

DIC is uncontrolled activation of coagulation that causes microvascular clotting → organ ischemia, then consumption of platelets/clotting factors → severe bleeding.

200

List 3 priority nursing actions for vaso-occlusive crisis. 

Hydration, Oxygen, and Pain Control.

300

Crackles, HTN, SOB during transfusion in older adult/HF suggests:

What is TACO?

300

Hgb 7.1 with hypotension + dizziness: the nurse should first suspect and assess for:

What is active bleeding/hypovolemic shock?

300

In thrombocytopenia, one of the most life-threatening signs of a complication is sudden severe headache + confusion, because it suggests:

What is intracranial hemorrhage? 


300

A nurse is caring for a client with platelets 12,000/mm³. List at least 6 thrombocytopenic (bleeding) precautions that should be implemented.

  • Avoid IM injections and minimize venipunctures 

  • No rectal temps, enemas, suppositories

  • Use soft toothbrush / oral swabs (avoid flossing if bleeding risk)

  • Use electric razor (no blades)

  • Avoid aspirin/NSAIDs (increases bleeding risk)

  • Stool softeners to avoid straining/Valsalva

  • Fall precautions / avoid contact sports

  • Monitor for bleeding: petechiae, purpura, hematuria, melena, gum/nose bleeding

  • No invasive procedures unless essential

300

Sickle Cell Disease + fever + hypoxia + chest pain → suspect this life-threatening complication.

What is acute chest syndrome?

400

Child with Sickle Cell Disease becomes suddenly weak/lethargic, tachycardic, with enlarged spleen.  

What is Splenic sequestration crisis?

400

This is how iron is absorbed best: 

What to avoid when taking iron:

With Vitamin C (orange juice), 1 hour before meals or 2 hours after meals. 

*Avoid taking with milk/dairy, calcium/antacids

*Education on black stools when taking iron

400

A septic patient begins oozing from IV sites and has hematuria. This points most strongly to:

What is DIC? 


400

A chemotherapy client has an ANC of 420/mm³. List at least 6 neutropenic precautions the nurse should implement.

  • Strict hand hygiene 

  • Private room 

  • Screen visitors: no sick contacts, limit visitors

  • No fresh flowers/plants

  • Avoid raw/undercooked foods; follow neutropenic diet guidelines (no sushi, runny eggs, unwashed produce)

  • Daily temp monitoring; report fever ≥ 100.4°F immediately

  • Use aseptic technique for lines; monitor IV site closely

400

A provider orders hydroxyurea for sickle cell disease. Which lab is most important to monitor for adverse effects?

What is CBC with differential (neutropenia/myelosuppression risk)?

500

I cause both thrombosis and bleeding simultaneously. I am often triggered by conditions like sepsis or trauma.

What is Disseminated Intravascular Coagulation (DIC)?

500

This explains how chronic kidney disease causes anemia.

Chronic kidney disease (CKD) causes anemia primarily because the kidneys stop making enough erythropoietin (EPO) - the hormone that tells the bone marrow to produce red blood cells.

500

Platelets 9,000. Patient has oozing from gums. VS stable. What is the nurse’s FIRST action?

Initiate bleeding precautions immediately

500

Child with SCD develops sudden pallor, tachycardia, lethargy, and rapidly enlarging LUQ abdomen. Hgb drops sharply with reticulocytes ↑.
What is it + priority action?

Splenic sequestration crisis. The spleen rapidly enlarges because it’s filling with blood The circulating blood volume drops → hypovolemia / shock Hemoglobin drops fast, Bone marrow tries to compensate → reticulocyte count increases.

Treat it like shock: Oxygen, Large-bore IV access, Fluids and urgent blood transfusion per provider protocol, Rapid response/provider STAT, Continuous VS monitoring 

500

Sickle Cell Disease patient has SpO₂ 88% with fever and chest pain. The nurse’s FIRST action is:

Apply oxygen