Modified Knotts
Blood Chemistry
Blood Chemistry
100

This is the primary purpose of the Modified Knott’s test—to concentrate and identify these larval stages of heartworm in a blood sample.

microfilariae

100

This byproduct of muscle metabolism is filtered by the glomeruli and is considered a more specific indicator of kidney disease than BUN in dogs and cats.

Creatinine

100

This value represents the concentration of nitrogen in the blood that comes from the waste product urea; it can be falsely elevated by a high-protein meal or GI bleeding.

BUN

200

This specific chemical is added to the blood sample to lyse the red blood cells, making it easier to see the parasites under the microscope.

2% Formalin

200

This electrolyte is often dangerously elevated (hyperkalemia) in male cats suffering from a urethral obstruction, leading to life-threatening bradycardia.

Potassium

200

This yellow-pigmented byproduct of hemoglobin breakdown is measured to evaluate liver function and patency of the bile duct; elevations cause icterus.

Bilirubin

300

Is the modified knotts test old

yes

300

Often elevated in cases of cholestasis or young growing animals, this enzyme can be induced by glucocorticoids (steroids) specifically in the dog.

ALP

300

This test measures the average glucose concentration over the previous 2-3 weeks and is essential for distinguishing "stress hyperglycemia" from true Diabetes Mellitus in cats.

Fructosamine test

400

Is the modified knotts test dumb in the modern age.

What is      yes.

400

This "leakage enzyme" is highly liver-specific in dogs and cats; elevations typically indicate direct damage to the hepatocytes.

ALT

400

In cats, this kidney marker often rises earlier than Creatinine, potentially detecting chronic kidney disease (CKD) when only 25% of kidney function is lost.

SDMA

500

Should you preform the test if your doctor askes you to

I mean maybe what kind of rapor do we have with this doctor.

500

Usually, BUN and Creatinine don't show significant elevations until roughly what precent of nephron function is compromised!

75%

500

This is the most abundant plasma protein; a decrease (hypoalbuminemia) can lead to peripheral edema due to a loss of oncotic pressure.

Albumin