Category 1
Anemia is a sign of an underlying disease or deficiency (T/F)?
True
Name 3 labs that should be ordered with initial anemia work up
CBC
Reticulocyte count
Peripheral Smear
Venous stasis, hyper coagulability, and vascular injury are all predisposing factors to a venous thrombus known as _______________?
Virchow's Triad
You have determined that a patient has microcytic anemia, what is the next lab that you should collect?
Ferritin
What is a reticulocyte?
a young, immature non-nucleated RBC
Anemia is defined as a hemoglobin less than ____ in a male adult
<13g/dL
what are 4 medications that can inhibit platelet function?
1. ASA
2. NSAIDs
3. Plavix
4. SSRI
Who is SpongeBob's best friend?
Patrick Star
A vegan patient would like to know what supplement is important for them to take?
B12
what condition is consistent with small, flat, red, discrete areas of skin bleeding usually occurring in dependent areas of the body?
Petechiae
Name 3 key nutrients essential for normal erythropoiesis
Iron
Vitamin B12
Folate
You are suspicious a female patient with menorrhagia may have Von Willebrand disease, what labs would you want to collect? (5)
1. CBC
2. PT, aPTT (usually normal)
3. Plasma VW factor
4. Plasma VWF activity
5. Factor VIII activity
What is PERC?
Pulmonary Embolic Rule-out Criteria
Which lab is not used for a bleeding disorder?
peripheral smear
Factor V Leiden
Prothrombin Time (PT)
Activated partial thromboplastin (aPTT)
Factor V Leiden
Which of the following is not a clotting disorder?
Factor V Leiden
Lupus anticoagulant mutation
Von Willebrand's
Protein C or S deficiency
Antithrombin deficiency
Von Willebrands
The primary regulatory hormone in erythropoiesis is ________?
EPO
What bleeding disorder will have a normal PT, prolonged aPTT, and a low level of activity of factor VII OR a low factor IX?
Hemophilia
A 36 year old obese female patient on birth control presents with right lower extremity edema, redness, and tenderness. You have a high suspicion for a DVT, what diagnostic test do you order?
US
A female patient comes to see you with petechiae and fatigue; she has a normal Hgb, lowered platelet count, and normal RBC count
Immune (idiopathic) thrombocytopenia purpura
A 32yo female of Mediterranean ancestry has a lowered hemoglobin, lowered Hct, elevated RBC, lowered MCV, and lowered RDW; what are you suspecting?
Beta thalassemia minor
Name 3 signs you may find on assessment in a patient with anemia
Pallor conjunctiva
Jaundice (hemolytic anemia)
Lymphadenopathy
Bone tenderness
Petechiae
Ecchymosis
You suspect a patient may have thrombocytopenia, what labs should you collect (4)
1. CBC
2. peripheral smear
3. HIV
4. Hepatitis C virus
What are common causes of thrombocytopenia?
1. pregnancy
2. bone marrow suppression with chemotherapy/radiation therapy
3. chronic alcohol abuse
4. chronic liver disease
5. DIC
6. heparin induced thrombocytopenia
7. ITP (Immune thrombocytopenia purpura)
8. viral infection
9. sepsis
10.preeclampsia/ HELP syndrome
A 76yo female presents with fatigue, spoon-shaped nails, lowered Hgb, lowered MCV, and increased RDW; what is your critical diagnosis to determine? (GI Bleed, malabsorption, chronic ileitis, or pernicious anemia)
GI bleed
A 68yo female patient has a 6mo history of severe peripheral neuropathy and oral irritation. You note a profound murmur and conjunctival pallor. What is you suspicion?
B12 deficiency