Plasma Cell
Area adjacent to the nucleus of a plasma cell
golgi; perinuclear halo
Hemoglobin form not measured by cyanmethemoglobin
Sulfhemoglobin
Neutrophils and RBCs appear blue
Overstained
pH too alkaline
A patient with normal Hgb and WBC counts, persistently elevated platelet counts (>100,000,000/ul), increased marrow megakaryocytes and a history of frequent bleeding most likely has:
ET
RBC inclusion only visible with supra vital stain
Heinz Body
Major peripheral smear finding associated with plasma cell disorders
Rouleaux
Levels of CO2 and 2,3 DPG associated with right shift.
Associated pH with a right shift.
Increased
Acidic
3 causes of platelet clumps
Short draw
Clotted sample
EDTA-induced
ET
2 diseases associated with defective ROS production by neutrophils
IMF
CGD
A term used to describe a mature RBC that contains iron granules or deposits
Siderocyte
4 common features of all P.C. disorders
Rouleaux
Increased ESR
Hyperviscosity
Bence jones
M-spike
P.C. (or plasmacytoid) in B.M.
3 interferences of the cyanmethemoglobin method
High WBC
Lipemia
Lyse resistant RBCs (sickle cells)
4 artifact causes of burr cells
Artifact:
Excess EDTA
H2O contamination
Slow drying
Increased humidity
Blowing
Old Sample
Polycythemia associated with:
Hgb 25 g/dL
Hct 60%
O2 Saturation: normal
Smear: Microspherocytes, schistocytes
Relative Polycythemia
3 peripheral findings associated with Hgb SS
Sickle cells
Target cells
Schistocytes
Polychromasia
nRBCs
P.C. associated with plasmacytoid lymphs
Waldenstroms
A cellulose acetate was performed on a stillborn infant revealed a single band that migrated further toward the anode than the Hgb A control. What is the composition of this band?
4 gene deletion-hydrous fetalis
Hemoglobin barts (gamma)
Megaloblastic triad
Hypersegs
MCV > 100 fL
Macroovalocytes
(Bonus-Pancytopenia)
Which of the following is not a cause of absolute secondary erythrocytosis?
Defective cardiac or pulmonary function
High altitude adjustment
Dehydration due to diuretic use
Hemoglobin with increased oxygen affinity
Dehydration due to diuretic use
Which of the following blood findings LEAST likely correlates with the presence of ringed sideroblasts in the bone marrow?
Pappenheimer bodies
Basophilic stippling
Decreased TIBC
Siderocytes
Decreased TIBC
P.C. disorder associated with Russell Bodies
Multiple Myeloma
A cellulose acetate revealed a band in the Hgb S position. This band was 95%. The peripheral smear showed 70% target cells and the solubility test was negative.
Based on the information, what is the hemoglobin?
Hemoglobin D
An adult WBC count was 4.0x103/ul. The differential was: PMNs 25%, bands 5%, lymphs 65% and monocytes 5%.
There is:
absolute lymphocytosis
relative lymphocytosis
both relative and absolute
relative
4 differences between CML and leukemia reaction
Toxic changes (L)
Ph' chromosome (C)
Basophilia/Eosinophila (C)
LAP increased (L) LAP decreased (C)
4 Poikilocytosis/slide abnormalities associated with a short draw
Crenated WBC
Crenated RBC
Platelet clumps
Giant platelets
Platelet sat elitism