Heme Stem Cells
Multiple Myeloma and Related Disorders
Platelets/Bleeding
RBCs
Thrombotic Disorders
It's All Latin to Me
100
Class of drugs that target BCR-ABL oncoprotein
Tyrosine Kinase Inhibitors
100
M protein level in MGUS
< 3g/dL
100
Treatment for Type I Heparin-induced thrombocytopenia
Nothing
100
Primary treatment for Cold Agglutinin Disease
Avoid Cold
100
In Factor V Leiden mutation, what is FVL resistant to?
Cleavage by activated protein C
100
Right - Sided heart failure from lung disease
Cor Pulmonale
200
Name either of the first line agents for Polycythemia Vera
Hydroxyurea or Interferon-alpha
200
Preferred method of detecting lytic bone lesions in Plasma Cell Dyscrasias
Whole-body low-dose CT
200
Most patients have autoantibodies to what metalloprotease leading to TTP?
ADAMTS13
200
What's the diagnosis: fatigue, microcytic anemia, headache, and eating crunchy foodstuffs
Iron Deficiency
200
How long to continue anticoagulation in patients with a provoked thrombosis and reversible risk factors?
3-6 months
200
Seizure lasting longer than 5 min
Status Epilepticus
300
Name eosinophilia causes (mnemonic is CHINA)
Collagen Vascular Disease (eosinophilic granulomatosis)
Helminthic (parasites)
Idiopathic
Neoplasia
Allergy/Atopy/Asthma/Also drugs...
300
Emergent treatment for hyperviscosity in Waldenstrom Macroglobulinemia
Plasmapheresis
300
Lab findings in DIC (Platelet levels, PTT, PT, Fibrinogen, and D-dimer)
Low platelets and fibrinogen
Elevated PTT, PT, and D-Dimer
300
Recommended nutritional supplement for patients with thalassemia
Folate
Patients need to avoid iron as they absorb it more efficiently and are mores susceptible to iron overload
300
Criteria for lower extremity superficial vein thrombosis that warrants anticoagulation (give 2 of the 3)
5cm in length, close to deep venous system, or other risk factors (cancer/previous VTE/etc)
300
The bad breath that is associated with end-stage liver disease
Fetor hepaticus
400
Goal Hemoglobin in patients undergoing dialysis
<10-11 g/dL (to avoid Cardiovascular outcomes)
400
Up to 10% of patients with HFpEF have what underlying amyloidosis?
Wild-type Transthyretin (previously senile systemic)
400
Why won't Factor VIII concentrate work in Acquired Hemophilia A?
Autoantibody blocks VIII activity - must bypass Factor VIII for Tx w/ recombinant activated Factor VII
400
What cofactor deficiency will result in RBCs designated by the black arrow
NADPH
No NADPH -> oxidative stress -> Heinz Bodies -> splenic macrophages form bite cells
400
Which DOAC is safe in dialysis
Apixaban
400
Massive deep vein thrombosis causing near-total venous outflow obstruction, leading to severe edema, cyanosis, and severe pain
Phlegmasia Cerulea Dolens
500
All-trans retinoic acid is used in which leukemia?
Acute Myeloid (AML)
500
Name the immunoglobulins associated with its respective type of cryoglobulinemia
(Will give hint if needed)
I: IgM (associated with PCDs)
II/III: Polyclonal IgG and mono/polyclonal IgM (usually infectious or connective tissue disorders)
500
Tx for patient with asymptomatic ITP and platelet count of 21,000
Glucocorticoids (Prednisone/Dexamethasone)
500
Vaccination needed before start eculizumab or rovelizumab for Paroxysmal Nocturnal Hemoglobinuria
Meningococcal
500
Reversal agent for heparin and LMWH
Protamine sulfate
500
Fatal Arrythmia triggered by blunt trauma to the chest
Commotio Cordis