A 23-year-old woman presents with fever and abdominal pain. Her family notes that she has been confused for the last 24 hours. Labs demonstrate WBC: 6.7 Hgb: 8.9 Plts: 15 Creatinine 1.7. Your diagnosis.
What is TTP?
100
This eponymous plasma cell dyscrasia, also known as lymphoplasmacytic lymphoma, is associated with high levels of circulating IgM.
What is Waldenström's Macroglobulinemia?
100
A 45-year-old man presents with fevers, chills, cough for two weeks and is diagnosed with pneumonia. Labs demonstrate WBC 0.5, Hgb 7.9, Platelets 54.
What is acute leukemia?
100
DIC does not occur in isolation. These are three of the most common comorbid conditions.
What are sepsis, malignancy, trauma, obstetrical complications, or intravascular hemolysis?
100
This attending used to casually jog 20 miles to her shifts at Lahey.
Who is Thea James?
200
Antibodies to this enzyme prevent cleavage of Von Willebrand factor in TTP.
What is ADAMTS13?
200
This is the high-specificity test for Heparin Induced Thrombocytopenia.
What is the serotonin release assay?
200
If diagnosing acute leukemia, don't forget to screen for this possible comorbid coagulopathy.
What is DIC?
200
Two common lab abnormalities in DIC.
What are thrombocytopenia, low fibrinogen, prolonged PT/aPTT, low platelets, elevated D-dimer.
200
This attending once trounced Holland 87-0 in a world cup match.
Who is Kerry McCabe?
300
A 65-year-old hospitalized after a CABG 7 days ago complains of left leg swelling and pain. His labs demonstrate platelet count of 25k. Your diagnosis.
What is heparin induced thrombocytopenia/thrombosis?
300
A 60-year-old woman presents with new onset blurry vision and headache. She has oozing from her gums. WBC 10, Hgb 9, Plts 196. Cr 0.8, K+ 3.6, albumin 3.0, total protein 12.5.
What is hyperviscosity syndrome?
300
Your well-appearing patient undergoing cisplatin/gemcitabine therapy for cholangiocarcinoma presents complaining of numbness in a stocking-glove distribution.
What is chemotherapy-induced peripheral neuropathy?
300
Exposure of blood to this procoagulant may be an important first step in the pathogenesis of DIC.
What is tissue factor?
300
This attending was previously a graceful ballet performer.
Who is Jeff Schneider?
400
The typical timeframe for developing HIT after initial heparin exposure.
What is 5-10 days?
400
A 78-year-old woman with a recent diagnosis of AML presents with worsening fatigue and new shortness of breath. She is tachycardic with a room air SpO2 of 85%. WBC 180, Hgb 7.4, Plts 48.
What is leukostasis?
400
The pathologic finding on this peripheral smear.
What are Auer rods?
400
Consider transfusing this blood product for patients with low fibrinogen levels.
What is cryoprecipitate?
400
The title of this 2008 Liz Mitchell album.
What is "Not the Whether of Summer."
500
In TTP, call the unit, temporize with this product while preparing for this lifesaving therapy.
What are fresh frozen plasma and plasmapharesis?
500
A treatment strategy for leukemia-associated leukostasis.
What are cytoreduction, chemotherapy, or leukapharesis?
500
This subset of AML carries a high early mortality, demanding treatment before molecular diagnosis.
What is acute promyelocytic leukemia?
500
This skin finding in DIC:
What is purpura fulminans?
500
This attending was previously an Olive Garden Waiter. More soup and breadsticks, please!