Antiplatelet Agents
What is an over the counter antiplatelet?
What is baby aspirin?
What NSAID is known to have a drug interaction with Warfarin?
What is Acetylsalicylic acid (ASA, Aspirin)
What is another term commonly used for Anticoagulants?
What are blood thinners
What is the goal with fibrinolytic therapy?
What is to dissolve blood clots present arteries or veins
What is the basic definition of hemostasis?
What is process that stops bleeding from a blood vessel
Which type of clots do antiplatelet drugs target compared to anticoagulant drugs?
What are arterial clots (anticoagulants target venous clots)
In general how does Warfarin work?
What is blocks the formation of certain clotting factors which decreases the bodies ability to form blood clots?
What happens if a blood clot gets into the blood vessels?
What is a heart attack or stroke
How are fibrinolytics administered?
What is IV or catheter
How many stages are involved in hemostasis?
What is 4 stages
Clopidogrel is metabolized by what CYP450 enzyme?
What is CY2C19
True or False: Preventing clotting is the goal of Warfarin therapy?
False, it is only to decrease the clotting tendency and not to prevent clotting all together
True or False: Anticoagulants can break up blood clots?
False, they can only prevent them and help existing blood clots from increasing in size
What test can be used to check if the blood clot is dissolving during thrombolytic therapy?
What are imagining tests like MRI or CT scans
What is the blood test that measures the time that it takes for blood to clot?
What is Prothrombin Time test or Protime (PT)
When should should antiplatelet therapy be started after an ischemic stroke?
What is 24-48 hours
What lab value must be tested frequently through blood work in those taking Warfarin to ensure there is no increase risk of bleeding?
What is International normalized ratio (INR)
What are the two direct thrombin inhibitors?
What are Dabigatran and Heparin
What is the mechanism of fibrinolytic therapy?
What is multi-step process that acts as a protective mechanism to control hemorrhage?
What is the hemostatic cascade
In which type of strokes are antiplatelets used as first line therapy?
What is noncardioembolic ischemic stroke of transient ischemic attack (TIA)
Name the vitamin found in leafy greens that decrease the effects of warfarin?
What is Vitamin K?
Which drugs inhibit factor Xa to reduce prothrombin activation?
What are heparins (UFH, LMWH), fondaparinux, rivaroxaban?
How is alteplase produced?
What is recombinant DNA technology
With in how many minutes after trauma to blood vessels does vasoconstriction occur from a vascular spasm?
What is 30 minutes