Entry
Replication
Latency
Reactivation
Random Facts
100

What part of the body does HSV enter through?

Skin or mucous membranes

100

Where does HSV send its DNA inside the cell?

The nucleus

100

Where does HSV hide when it's inactive?

Sensory Ganglion

100

What might trigger HSV to wake up?

Stress, illness, sunburn

100

What does HSV stand for?

Herpes Simplex Virus

200

What proteins help HSV stick to a cell?

Glycoproteins (e.g., gD)

200

What gets copied to make more viruses?

Viral DNA

200

True or False: HSV hides in blood cells.

False

200

What are common signs of reactivation?

Cold sores or genital lesions

200

Name one type of HSV.

HSV1 or HSV 2

300

What happens when HSV fuses with the cell membrane?

The virus enters the cell

300

What does the nucleus do with HSV DNA?

Copies viral parts & assembles viruses

300

Why is latency important to HSV?

It lets the virus avoid the immune system

300

What makes HSV hard to cure?

It hides from the immune system

300

How many people under 50 have HSV-1 worldwide (est.)?

Over 3.7 billion

400

What kind of cell does HSV enter? (Be specific!)

Epithelial cells

400

What are the 3 stages of HSV gene expression?

Immediate Early, Early, Late genes

400

Can HSV be spread during latency?

Yes

400

What’s a common trigger in young people?

Stress, hormonal changes, lack of sleep

400

Is HSV a DNA or RNA virus?

DNA