cOCANE??
What medical issues other than ASD can microbes help regulate?
depression and anxiety
the gut microbiota
"soggy, three pound lump of cells"
the brain
Define "high-functioning autism"
Considered controversial due to the fact that it tends to minimize struggles of those with ASD, it defines those who experience symptoms of ASD (including social difficulties) without intellectual disability. In many cases, those with high-functioning autism only receive a diagnosis after personally consulting a professional
Along with social deficits, repetitive behaviors, and language difficulties, what are ASD patients 3.5 times more likely to experience than neurotypicals?
gastrointestinal issues
Where is it suggested that Parkinson's Disease starts in the body?
the gut
The overuse of what contributed to the decimation of the human gut microbiome?
antibiotics
Subsequent to wandering, what accounted for 91% of deaths reported for kids with autism between 2009 and 2011?
drowning
What were three mice variations that resulted in ASD-like symptoms?
High-fat diet (HFD), "double negative" Shank3B, valproic acid (VPA), BTBR
What particularly influences the development of the body's nervous system?
metabolic and immune states
What controls how humans think, behave, and feel?
neurotransmitters
Who or what is the thing from the jeopardy slide?
TBH creature, autism creature, "yippee"
What surgical procedure did the mice undergo?
bilateral subdiaphragmatic vagotomy
During pregnancy, what increases the odds of an ASD diagnosis in the child (not including a high-fat diet)?
intense infection with a high fever
What has contributed to a 25% increased risk of diseases including asthma, IBS, obesity, and immune deficiencies?
cesarean sections
Within the community, what are autistic fixations called?
special interests
What restored social behavior in vagotomized Shank3b-/- mice?
intranasal oxytocin treatments
What example acts as a vehicle for direct signaling from the gut microbiome to the nervous system?
short-chain fatty acids
When the vagus nerve is severed, how are the intestines affected?
they're not >:)
the intestines continue to function
What brain disorder is autism historically associated with?
schizophrenia