When a single gene has more than one effect on phenotype, it is known as this:
What is Pleiotropy?
100
Metabolic syndrome is diagnosed as a combination of which four conditions:
What are hypertension, hyperglycemia, hypercholesterolemia, excessive fat around the waist?
100
This chronic form of low-level depression can only be diagnosed after this many days:
What is 730 days (or 2 years)?
100
This nucleotide is made last in the process of DNA synthesis:
What is dATP?
100
This cytokine is responsible for a cancer patient's 'cachectic' appearance:
What is TNF-alpha?
200
The odds of inheriting a disease that primarily affects the structural proteins of the body, if one of your parents are affected, is this percentage:
What is 50%?
200
This vitamin present in the skin will absorb UVB rays from the sun:
What is 7-dehydrocholesterol (pro-vitamin D3)
200
New mothers who develop feelings of estrangement or detachment from their newborn are typically diagnosed with this condition:
What is postpartum depression?
200
Poikyloderma and hyperpigmentation and common findings in patients with a deficiency of this dimer excising enzyme:
What is UV endonuclease?
200
The two proteins of the HPV virus, E6 and E7, are able to bind to and inactive these two cellular tumor suppressors:
What is p53 and pRB?
300
This disease, which presents with elevated IgE, formation of abscesses, and coarse facial features, is characterized by a decrease in the production of this interferon:
What is INF-gamma?
300
If a patient is given warfarin, it can cause the depletion of protein C in this many hours:
What is 30hr?
300
This specific dopamine receptor, when blocked, has strong anti-emetic properties:
What is the D2 receptor?
300
This chemotherapeutic agent is known to inhibit the activity of topoisomerase 2:
What is Etoposide?
300
Non-Hodgkin's lymphoma is characterized by the over expression of the anti-apoptotic gene product known as this:
What is BCL2? This leads to tumor formation.
400
These two important proteins involved in retinoblastoma are involved in the cell cycle and play a role in the phosphorylation of proteins in the late G1 phase:
What are CDK's and Cyclins?
400
At 10 times the daily recommended value, vitamin A toxicity can cause patients to suffer from injury to the liver, thus leading to this finding:
What is cirrhosis?
400
The 1st line treatment for panic disorder has this specific deficiency as its main side-effect:
What is decreased libido or anorgasmia?
400
The CAAT box is located at this location, while the TATA box is located at this location:
What is -35 and -10?
400
This cancer antigen is associated with as many as 60% of all cancers:
What is p53?
500
In achondroplasia, there is a replacement of the amino acid glycine with arginine at this specific position on the gene sequence:
What is the 308th position on the gene?
500
These are the six (6) findings associated with Wernicke-Korsakoff syndrome:
What is: 1. Anterograde amnesia, 2. Retrograde amnesia, 3. Meager conversation content, 4. Confabulations, 5. Apathy, 6. Lack of insight?
500
With significant ingestion of Acetaminophen, sulfation and glucuronide conjugation becomes saturated and there is an accumulation of this toxic compound that can damage the liver:
What is NAPQI?
500
At which biochemical point does the nucleophilic attack leading to mRNA splicing occur?
What is the 2'OH point (a predetermined branch point)?
500
This type of AML is associated with megakaryocytes and trisomy 21: