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Microbiology
Epidemiology
Pathology
Treatment, Prevention and Immunology
History, Culture and Psychology
100
What causes epidemic typhus?
Rickettsia typhi
100
Name 3 symptoms of both diseases.
Fever, chills, headache, rash, delirium
100
Name two non-pharmacological ways to avoid getting typhus.
Insecticide, sanitation, hand washing, avoid people with lice or fleas
100
What is the name of the physician that studied typhoid in 1856
William Budd
200
Where does typhoid enter the body?
The digestive tract
200
Why is Mary Mallon significant in relation to to typhoid?
She is associated with 53 cases and 3 deaths. She was known as "Typhoid Mary"
200
Describe the typhoid state.
Staring apathetic appearence with half closed eyes.
200
Which has a vaccine available?
Typhoid
200
How did Typhoid Mary die and after how long?
She died in quarantine after 26 years.
300
Where does typhus enter the body
What is the irritated bite site
300
What colony had an outbreak of typhoid in the early 1600's?
Jamestown, Virginia
300
What are most symptoms of typhoid caused by
Endotoxin
300
What are the options for a vaccine and how are they taken?
What is inactive (injection) and active (oral).
400
What is the mechanism that salmonella uses to get a host cell to engulf it?
Type III injector system
400
How many cases of typhus were there during WWI?
30 million
400
When does the typhus rash begin?
The 4th or 5th day
400
Name two of the drugs that can be taken for typhus.
Doxycycline, tetracyclines and chloramphenicol
400
When and where was the first reliable description of typhus?
The Spanish siege in Granada in 1498
500
What cells specifically does the typhus bacteria attack?
The cells that line the blood vessels
500
Which months is typhus more likely to be spread?
The cold months
500
Where on the body does the typhus rash begin?
Near your armpits and trunk
500
Is the vaccine offered for everyone? If not, who specifically is it suggested for? How effective is the vaccine?
No, only high risk people such as travelers, people who work with S. Typhi, or people in close contact with a carrier. It is only 50-80% effective
500
Name two things that the physician who studied typhoid concluded.
Typhoid is contagious, convalescent patients could pass it on, and it could be contracted by drinking contaminated water or milk