The ART drug class recommended as initial HIV treatment that requires two of the same
What is
2 NRTIs (backbone)
100
Based on current guidelines, this is the only recommended drug for PrEP
What is Truvada?
100
When, after birth, should baby start receiving HIV prophylaxis?
Within 6 - 12 hours of delivery
100
This class of ARVs is harder to develop resistance to but can also cause hyperlipidemia
What is protease inhibitors?
200
Medication recommended for TB prophylaxis (latent TB) in HIV positive patients
What is isoniazid (INH)?
200
This test must be done before starting any patient on abacavir containing ART
What is HLA-B*5701?
200
PrEP patients must be tested for HIV this often
Before starting PrEP and then every 3 months
200
Perinatal drug of choice for HIV prophylaxis
What is zidovudine (AZT)?
(AZT + nevirapine for baby born to mother who received no ART)
200
The only HIV drug that cannot be used in the 1st six weeks of pregnancy
What is Sustiva (efavirenz)? (1 of the 3 drug in Atripla)
300
This is the medication recommended for PCP prophylaxis in HIV positive patients
What is Bactrim DS once daily?
300
The other ART used most often as inintal therapy together with 2 NRTIs
What are integrase inhibitors
300
The amount of time after exposure that post exposure prophylaxis (PEP) must be started
What is as soon as possible but within 72 hours after exposure.
300
The duration of therapy for HIV prophylaxis in an HIV exposed infant
What is 4 to 6 weeks?
300
Lab tests refered to as "Top 4"
What is viral load, CD4 count, CBC, CMP?
400
This is the first medication choice for MAC prophylaxis in HIV positive patients
What is Azithromycin 1200mg once weekly?
400
The protease inhibitor for initial treatment of HIV
What is darunavir boosted with ritonavir?
400
The duration of post exposure prophylaxis (PEP) for sexual assault
What is 28 days?
400
Viral Load where intrapartum (during delivery) zidovudine is not recommended according to guidelines
What is a viral load < 1000
A C-section isn't necessary either
400
This test is done to determine if a patient is resistant to HIV medications
What is an HIV genotype?
It is done before starting therapy and at treatment failure
500
Under what CD4 count would a patient need prophylaxis for MAC?
Under 50
500
Name 3 factors that may contribute to HIV therapy faliure
1. Non-adherence
2. Mutations/resistance
3. Drug-drug interactions or other PK issues (i.e. pregnancy)
4. Suboptimal drug regimen
500
The medications used in the PEP protocol at NCH
What is Truvada + Isentress? (different medications may be used if source of exposure can be tested for current ART use, resistence, etc)
500
Class of HIV medications that may need adjusted in the 2nd and 3rd trimester due to an increased volume of distribution
What are Protease Inhibitors
500
Vaccinations contraindicated in HIV patients
What is MMR, and Varicella? (only if CD4 count is 200 or lower).
All vaccines except for flu should be held until the CD4 is >200 due in inability to respond