frontline therapy for HOCM includes titration of heart rate to 60-65 with this medication
What is a Beta Blocker
100
the original surgical technique used to treat HOCM (procedure, surgeon and brief explantation)
What is Bigelow's Myotomy?
what is myotomy with finger fracture?
100
apposition of these two structures leads to LVOT obstruction in HOCM
What are the anterior leaflet of the mitral valve and LV septum?
100
route of exposure for treatment of Yamaguchi's disease
What is apical ventriculotomy?
200
Chance the offspring of a patient with HCM will develop this disease
What is 50%?
200
This calcium channle blocker is an acceptable second line agent to treat symptomatic HOCM
What is Verapamil?
200
two parallel septal incisions with removal of a rectangular piece of septal muscle
What is the Morrow Procedure?
200
Video daily double
What is the Brockenbrough Effect?
200
LVOT gradient above which survival is reduced
What is 30 mmHg?
300
Chromosome to which HCM has been localized
What is 14q1?
300
This class of calcium channel blocker should not be used to treat symptmatic HOCM
What is dihydropyradine (amlodipine, nifedipine)?
300
septal myectomy extending from the nadir of the right coronary cusp to just below the anterolateral commisure of the mitral valve to the depth of the base of the papillary muscles
What is the extended septal myectomy?
300
effect of Valsalva manuver on HOCM murmur
What is increases?
300
indications for surgery
What are optimal medical management with NHYA class 3-4 symptoms and LVOT gradient >50mmHg?
400
two of the most common genes mutations of which result in HCM
What are Beta Myosin Heavy Chain(MYH7), Myosin Binding Protein C3 (MBC3) or Tropinin T?
400
dual chamber pacing is a reasonable treatement for HOCM in these patients
who are patients with preexisting pacemakers?
(also acceptable: medically refractory symptomatic patients who are not candidates for Myectomy or alcohol septal ablation?)
400
2% and 20%
What is the incidence of heart block after septal myectomy and alcohol septal ablation?
400
aside from LVOT obstruction, this phenomenon contributes to symptomatology
What is SAM/MR?
400
accepted route of exposure in addition to transaortic and transapical
What is transmitral?
500
genetic terms which explain why some patients with mutations for HCM do not manifest the disease (name one)
What are variable expressivity and age related penetrance?
500
1) wall thickness of >30mm
2) Personal or family history of sudden death
3) unexplained syncope
4) documented nonsustained VT
What are indications for ICD implantation?
500
Denton Cooley's treatment for HOCM
What is mechanical MVR?
500
entities responsible for SAM with HOCM (name three)
What are:
redundant anterior MV leafelet?
anteriorly displaced papillary muscles?
Narrowing of the aortic-mitral angle?
Venturri Effect?