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What disease am I?
Menstrual cycle
Because we love Med Chem!
Infertility
Miscellaneous
100

Syndrome characterized by gonadotropin-dependent ovarian hyperandrogenism associated with anovulation and infertility.

What is polycystic ovary syndrome (PCOS)?

100
Hormone that stimulates granulosa cell growth.
What is follicle stimulating hormone (FSH)?
100

Hormone with non-aromatic A-ring and double-bonded oxygen (also on A-ring)

What is progesterone?

100
Gonadotropin purified from pregnant women's urine.
What is human chorionic gonadotropin (HCG)?
100

Non-hormonal intrauterine device (IUD)

What is ParaGard?

200
Can be caused by losing weight, resulting in no menstrual periods for at least 3 months.
What is secondary amenorrhea?
200
Hormones produced by theca cells that are converted into estrogens by granulosa cells.
What are androgens?
200

Most common synthetic form of estrogen in contraceptives

What is ethinyl estradiol?

200
Disease caused from ovary activation and leads to peritoneal fluid accumulation.
What is ovarian hyperstimulation syndrome (OHSS)?
200

This second messenger relaxes cavernosal smooth muscle and increases blood flow during an erection.

What is cGMP?

300
Excessive blood loss during menstruation.
What is menorrhagia?
300
Estrogen-dependent phase of the uterine cycle.
What is the proliferative phase?
300

Which two rings in the 17b-estradiol steroid scaffold are hydroxylated by metabolic enzymes?

What are A and D?

300
Estrogen receptor modulator that increases FSH production.
What is Clomiphene citrate (Clomid)?
300
The effect of Cetrorelix (Cetrotide) on pituitary function.
What is suppression of LH secretion?
400
Disease thought to be caused by retrograde menstruation and aggravated by inflammation.
What is endometriosis?
400
Hormone that de-sensitizes the endometrium to estrogens.
What is progesterone?
400

Term for a chemical group blocking accessibility to metabolic enzymes in certain regions of a drug molecule.

What is steric hindrance?

400

Testicular condition in which increased venous pressure disrupts countercurrent heat exchange, elevating intratesticular temperature and impairing Sertoli‑cell–dependent spermatogenesis.

What is varicocele?

400

Type of enzyme that modifies conjugated estrogens in order to yield the more potent agonist 17b-estradiol.

What are sulfatases?

500

Progressive condition characterized by androgen‑driven periurethral stromal and epithelial hyperplasia leading to lower urinary tract symptoms

What is benign prostatic hyperplasia (BPH)?

500

State in which ovarian follicular depletion eliminates estradiol‑mediated negative feedback, causing chronic elevation of FSH and LH and leading to vasomotor instability.

What is menopause?

500

Type of enzyme that modifies a chemical group on the D-ring of 17b-valerate to yield biologically active 17b-estradiol?

What is esterase?

500

Endocrine disorder in which disruption of hypothalamic dopaminergic inhibition leads to chronically elevated pituitary hormone levels that suppress GnRH pulsatility, ultimately impairing LH‑dependent testosterone production and Sertoli‑cell–mediated spermatogenesis.

What is hyperprolactinemia?

500

This PDE5 inhibitor has the longest half‑life (~18 hours), allowing once‑daily dosing.

What is Tadalafil?