Understanding Blot Clotting
What is the main function of platelets in the blood clotting process?
They help form a blood clot by sticking together and plugging holes in damaged blood vessels.
How can prolonged immobility, such as being bedridden for a long period, contribute to hypercoagulability?
Prolonged immobility slows down blood circulation.
This then increases the risk of blood clot formation, particularly in the legs (deep vein thrombosis).
Is the disorder inherited or is it developed through deficiencies?
Both. The disorder can either be inherited through a genetic mutation or developed through deficiencies.
Blood test that checks all aspects of blood
CBC Test
Why does our blood clot in the first place?
What role does obesity/smoking play in increasing the risk of hypercoagulable disorders?
Both damage blood vessels and increase clotting factor production.
Which of the following is an example of a genetic mutation that can lead to this blood disorder: Factor V Leiden mutation or Lenore F mutation?
Factor V Leiden mutation
used to examine platelets, WBCs, and RBCs
hint P__ B_ S__ (3 words)
Peripheral Blood Smear
Think back to the analogy in our presentation, what do the "cars" represent?
Red Blood Cells
How can pregnancy contribute to a hypercoagulable state?
Pregnancy (and other hormonal factors i.e. birth control pills, or hormone replacement therapy) raise estrogen levels, which can promote clotting.
Which of the following is an example of a deficiency that can lead to hypercoagulable blood disorder: Belius II deficiency OR Antithrombin III deficiency
Antithrombin III deficiency
Measures how many seconds it takes for a clot to form in blood sample
hint: ____ time
Prothrombin Time