I have a headache

Bloody TACS

100

CGRP monoclonal antibody approved for preventive treatment of cluster headache

Galcanezumab (Emgality) 300 mg monthly

200

Name the two TACs that respond absolutely to therapeutic doses of Indomethacin. Bonus: what is considered therapeutic dose of indomethacin

Paroxysmal Hemicrania

Hemicrania Continua

75 mg TID

300

Drug of choice for treating short-lasting unilateral neuralgiform headache (SUNCT)

lamotrigine

400

Duration of cluster headache attack

15-180 minutes

500

The autonomic features of lacrimation, rhinorrhea, and nasal congestion seen in TACs are due to activation of which nucleus?

parasympathetic outflow from the superior salivatory nucleus 

No Pressure

100

what imaging studies should be ordered in a patient presenting with suspected idiopathic intracranial hypertension?

MRI Brain + MRV Brain to rule out space occupying lesion, structural lesion, or venous sinus thrombosis

200

MRI Brain finding in patient with suspected CSF hypotension 

pachymeningeal enhancement

300

drugs associated with development of IIH (name 2)

tetracycline antibiotics

vitamin A derivatives (isotretinoin)

400

first step in management of suspected CSF leak 

nontargeted autologous high-volume epidural blood patch 

500

diagnostic test to identify leak site

CT myelography 

"sinus" up for a headache consult

100

thought to be a migraine precursor; characterized by micropsia, macropsia, metamorphopsia, teleopsia, pelopsia

Alice in Wonderland Syndrome

200

pain confined to a small circumscribed area of the scalp with no underlying structural lesion

nummular headache

300

severe unilateral periorbital headache with painful and restricted eye movements

Tolosa Hunt Syndrome (inflammation in region of cavernous sinus or superior orbital fissure)

400

CACNA1A gene mutation on chromosome c19q13

familial hemiplegic migraine 1 - cerebellar involvement (gaze evoked nystagmus, ataxia), prolonged hemiplegia

500

Migraine with aura + stroke + dementia and other neurodegenerative symptoms

Diagnosis? 

Gene mutation / chromosome?

diagnostic test?

CADASIL

NOTCH3 on c19q13.1

skin biopsy --> look for microangiopathy

a pain in the face

100

first line treatment for Trigeminal Neuralgia

bonus: 3 lab abnormalities to monitor for

Carbamazepine and Oxcarbazepine

hyponatremia, leukopenia, transaminitis

200

elongated styloid process causing compression of nearby structures resulting in throat pain, dysphagia, odynophagia, globus

Eagle Syndrome

300

paroxysmal deep, boring pain felt within the ear canal. Provoked by touching trigger zones in the ear canal 

nervus intermedius neuralgia

400

3 procedural options for patients with TN that have failed medical therapy

microvascular decompression

radiosurgery

balloon compression

500

Syncope associated with this syndrome results from activation of the carotid sinus, resulting in bradycardia and hypotension due to peripheral arterial vasodilation

glossopharyngeal neuralgia

drugs

100

triptan mechanism of action

bonus: name the 2 long acting triptans  

5HT 1B/D receptor agonist

nratriptan and frovatriptan 

200

atogepant mechanism of action

small molecule CGRP receptor antagonist

300

selective 5HT 1F receptor agonist

Lasmiditan (Reyvow)

400

acetazolamide mechanism of action 

carbonic anhydrase inhibitor results in decreased CSF production

500

side effects associated with erenumab (3)

injection site reaction, constipation (can be serious), new onset or worsening of existing hypertension