A Bug's Life
Toxin Turmoil
Antibiotic Chess
Viral Vortex
Fever Fallacy
Vital Vaccines
Board Nightmares
100

This gram-positive diplococcus is the most common cause of community-acquired pneumonia in adults.

What is Streptococcus pneumoniae?

100

This toxin causes rice-water stools by activating adenylate cyclase.

What is cholera toxin?

100

First-line treatment for uncomplicated cystitis in women.

What is Nitrofurantoin or Bactrim?

100

This virus causes erythema infectiosum.

What is parvovirus B19?

100

Fever, murmur, and positive blood cultures suggest this diagnosis.

What is infective endocarditis?

100

These type of vaccines are contraindicated in pregnancy.

Double points if you can name 2.

What are live-attenuated vaccines? (MMR; Hep A; Herpes Zoster)

100

Best initial test for suspected HIV infection.

What is HIV antigen/antibody combo assay?

200

This organism causes bullous impetigo and produces exfoliative toxin.

What is Staphylococcus aureus?

200

This Shiga-like toxin causes hemolytic uremic syndrome.

What is E. coli O157:H7 toxin?

200

This antibiotic is most strongly associated with QT prolongation.

What is a macrolide (e.g., azithromycin)?

200

This hepatitis virus is associated with polyarteritis nodosa.

What is hepatitis B virus?

200

Fever, headache, and nuchal rigidity require this immediate test (after CT if indicated).

What is lumbar puncture?

200

Recommended vaccine for adults ≥65 or immunocompromised to prevent pneumonia.

What is pneumococcal vaccine?

200

This infection causes “target” lesions and AV block.

What is Lyme disease?

300

A gardener with nodular lymphangitis after a thorn injury is infected with this organism.  

What is Sporothrix schenckii?

300

This toxin leads to pseudomembranous colitis after antibiotic exposure.

What is Clostridioides difficile toxin?

300

Drug of choice for neurosyphilis. Route of administration. 

What is IV penicillin G?

300

This virus is associated with progressive multifocal leukoencephalopathy.

What is JC virus?

300

Fever and altered mental status with temporal lobe involvement on MRI.

What is HSV encephalitis?

300

Which vaccine is recommended during every pregnancy regardless of prior status?

What is Tdap?

300

Best initial test for suspected C. difficile infection.

What is stool toxin PCR?

400

Gram-positive branching rods, weakly acid-fast, causing brain abscesses in transplant patients.

What is Nocardia species?

400

This superantigen is responsible for toxic shock syndrome.

What is TSST-1?

400

This antifungal treats invasive aspergillosis.

What is voriconazole?

400

This virus is linked to Kaposi sarcoma.

What is HHV-8?

400

Most common infectious cause of FUO worldwide.

What is tuberculosis?

400

Minimum CD4 count required before administering MMR in HIV.

What is ≥200 cells/µL?

400

Subacute meningitis with cranial nerve palsies and basilar enhancement.

What is tuberculous meningitis?

500

Culture-negative endocarditis with exposure to farm animals suggests this organism.

What is Coxiella burnetii?

500

This toxin inhibits EF-2 leading to necrotizing pneumonia.

What is diphtheria toxin?

500

This drug is first-line for CMV retinitis in HIV patients.

What is ganciclovir?

500

Post-transplant patient with pneumonitis and periventricular calcifications.

What is CMV?

500

FUO with markedly elevated ferritin and negative infectious workup.

What is adult-onset Still disease?

500

Post-splenectomy vaccines should be administered against these three organisms.

What are Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b?

500

Cause of hematuria and bladder cancer years after freshwater exposure.

What is Schistosoma haematobium?