Duration of Therapy
This type of pneumonia should be treated for 7 days
HAP/VAP
In a patient with MRSA pneumonia, which antibiotic can not be used?
Daptomycin
A 1 y/o infant with NKDA presents with severe pain in the left ear and a fever of 102℉, the doctor confirms he has otitis media. What treatment should he receive?
Amoxicillin 90mg/kg/day divided in 2 doses
How should voriconazole be taken?
On an empty stomach
Is Linezolid bactericidal or bacteriostatic?
Bacteriostatic, it is cidal for Strep, Enterococcus and MRSA
What is the duration of therapy for meningitis infection caused by S. pneumoniae?
10 days
Name 3 major adverse events related to Vancomycin
Red man syndrome, nephrotoxicity, ototoxicity
For a 3 year old patient with signs and symptoms resembling meningitis, what bugs should be covered?
H. Flu, listeria, Neisseria meningitidis & strep. Pneumoniae
Can ceftriaxone be administered orally?
Parenterally only
It is preferred to use vancomycin in combination with piperacillin/tazobactam
False, risk of AKI
For how long do we treat with topical antibiotics a patient with impetigo?
5 days
Which electrolytes do we have to check in patients receiving treatment with amphotericin B?
Potassium & Magnesium
A patient with no prior history presented with unexplained 3 unformed stools in the last 24 hours. C.diff infection diagnosis was confirmed. What would you recommend?
Fidaxomicin 200mg BID for 10 days, Alternative: Vancomycin 125mg QID orally for 10 dyas
A patient with febrile neutropenia, should receive antibiotics prescribed within 3 h?
False, 30 mins to 1 hour
What is the difference between piperacillin/tazobactam and Cefepime
Cefepime lacks the coverage for anaerobes and enterococci
In necrotizing fasciitis, for how long do we keep Clindamycin?
72 hours
This antibiotic can cause thrombocytopenia if used for more than 14 days
Linezolid
The patient is diagnosed with Febrile Neutropenia. What antibiotic agent would you start the patient on and why?
Cefepime or Pip/Tazo or Carbapenem (no Erta) Need Anti-pseudomonal coverage
What can be done to minimize the incidence of infusion reactions with Amphoteracin?
Premedicate 30 mins prior to infusion with Benadryl, NSAID/APAP and hydration
What are the FDA approved indications of Omadacycline?
CAP and SSTI
What is the duration of therapy for endocarditis caused by highly penicillin resistant S. viridans in a patient with prosthetic valves?
6 weeks
Name 3 different adverse effects related to Fluoroquinolones
Qt prolongation, tendinitis & tendon rupture, aortic aneurysm rupture
A patient’s mycology culture came back positive for C.glabrata. The doctor would like to start caspofungin. What dose would you recommend?
70 mg loading then 50mg daily
Fluoroquinolones should not be administered with what type of products?
Dairy products, vitamins, antacids or other products containing polyvalent containing substances
Name 3 antibiotic classes that inhibit protein synthesis
Macrolides, Aminoglycosides, and Tetracyclines