Common side effects of tricyclic antidepressants include:
What is dry mouth, blurred vision, urinary retention, constipation?
Schedule of benzodiazepines
What is C-IV?
The boxed warning for antipsychotics:
What is increased risk of death in elderly patients with dementia-related psychosis?
Bupropion's contraindications:
What is seizure disorder, history of anorexia/bulimia, do not use with MAO inhibitors, or other bupropion products?
Common side effects of SSRIs:
What is sexual dysfunction, dry mouth, nausea, somnolence, insomnia, diaphoresis (dose-related), headache, dizziness?
The first-line drug classes used for anxiety:
SSRIs & SNRIs
Side effects of benzodiazepines
What is somnolence, dizziness, and ataxia?
Pharmacies must be certified and the patient must be enrolled in a REMS program to receive this medication:
What is Clozapine?
Natural product that may be beneficial in treating depression, but is a strong CYP3A4 inducer with many significant drug interactions:
What is St. John's Wort?
FDA-approved not only for depression, but also for peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain:
What is duloxetine?
Boxed warning for all antidepressants:
Safe for use in elderly patients with liver impairment
What are Lorazepam, Oxazepam, and Temazepam (LOT)?
Common side effects from second-generation antipsychotics:
What is metabolic syndrome (increased blood glucose, increased weight, and increased lipids)?
The therapeutic range for lithium:
What is 0.6 - 1.2 mEq/L (trough level)?
True/False: Paroxetine is one of the first-line agents for depression in pregnancy:
What is false?
Second-line drug treatment that takes 2-4 weeks for effect
What is buspirone?
Boxed warning for benzodiazapines:
What is use with opioids can result in sedation, respiratory depression, coma, and death?
A first-generation antipsychotic that is high-potency and is in the butyrophenone class:
What is haloperidol?
Key drugs that cause or worsen depression:
What are isotretinoin, clonidine, beta-blockers, systemic steroids, SSRIs, SNRIs, etc.?
Antipsychotic preferred in Parkinson's disease:
What is quetiapine?
Select drugs that cause anxiety:
What are Decongestants, Illicit drugs (LSD, cocaine, methamphetamine), Stimulants, Steroids, Antipsychotics?
Clonazepam and diazepam's contraindications:
What is severe liver impairment?
Baseline ANC must be ______ before initiating clozapine:
What is ≥ 1500/mm^3
______ requires slow titration due to the risk of a severe rash:
What is lamotrigene?
Used commonly in oncology and skilled nursing facilities to help with sleep, and to increase appetite:
What is mirtazapine?
Hypertensive crisis or serotonin syndrome can occur when MAO inhibitors are taken with these agents/foods:
What are SSRIs, SNRIs, and tyramine rich foods?
True or false: benzodiazepines should be used as monotherapy in the treatment of anxiety:
What is false?
Monitoring parameters for lithium:
What is serum lithium levels, renal function, and thyroid function (TSH, FT4)?
Most activating SSRI:
What is fluoxetine?
Brand name of olanzapine + fluoxetine?
The washout period needed if changing between SNRIs and MAO inhibitors:
What is 14 days is recommended?
______ is contraindicated with strong CYP3A4 inhibitors such as ketoconazole and itraconazole:
What is alprazolam?
Can be an irreversible side effect of antipsychotics:
What is tardive dyskinesia?
When treating bipolar disease in pregnancy, avoid these agents:
What are valproate, carbamazepine, and lithium?
True/False: In the treatment of bipolar disorder, antidepressants can induce or exacerbate a manic episode when used as monotherpy:
What is true, they should only be used in combination with a mood stabilizer?
Natural products that increase the bleeding risk when paired with SSRIs:
What is ginkgo, garlic, ginsing, glucosamine, ginger, and fish oils?
The antidote for benzodiazapine overdose
What is flumazenil?
Antipsychotics to avoid in patients with cardiac risk/QT risk:
What is ziprasidone, haloperidol, thioridazine, or chlorpromazine?
Severe side effect of trazodone in men:
What is priapism?
Not FDA approved for anxiety, but has shown benefit in patients with anxiety and neuropathic pain
What is pregabalin and gabapentin?
SSRI that is preferred in patients with cardiac risk:
What is sertraline?
Commonly used for alcohol withdrawal syndrome:
What is lorazepam, diazepam, and chlordiazepoxide?
The boxed warning for thioridazine:
What is QT prolongation?
These agents are approved as augmentation therapy with antidepressants for treatment-resistant depression:
What is buspirone, aripiprazole, olanzapine + fluoxetine, quetiapine ER, and brexpiprazole?
Three MAO inhibitors:
What is Isocarboxazid (Marplan), Phenelzine (Nardil), and Tranylcypromine (Parnate)?
Max daily dose of citalopram in elderly (> 60 years):
What is 20 mg/day due to increased risk of QT prolongation?
Brand name of clorazepate:
What is Tranxene-T?
The first medication approved for treatment of tardive dyskinesia:
What is valbenazine (Ingrezza)?
______ has the most favorable safety profile in pregnancy when treating bipolar disease, but use is limited due to being only FDA approved for bipolar depression
What is lurasidone (Latuda)?
Key drugs contraindicated with MAO inhibitors that increase serotonin:
What is linezolid, lithium, tramadol, opioids, St. John's wort, SSRIs, SNRIs, mirtazapine, trazodone, triptans, buspirone, and dextromethorphan?