My neck, my back, my anxiety attack
Take a ride in my Benzo
We're all mad here
More espresso, less depresso
Going down the rabbit hole
100

Common side effects of tricyclic antidepressants include:

What is dry mouth, blurred vision, urinary retention, constipation?

100

Schedule of benzodiazepines 

What is C-IV?

100

The boxed warning for antipsychotics:

What is increased risk of death in elderly patients with dementia-related psychosis?

100

Bupropion's contraindications:

What is seizure disorder, history of anorexia/bulimia, do not use with MAO inhibitors, or other bupropion products?

100

Common side effects of SSRIs:

What is sexual dysfunction, dry mouth, nausea, somnolence, insomnia, diaphoresis (dose-related), headache, dizziness?

200

The first-line drug classes used for anxiety:

SSRIs & SNRIs

200

Side effects of benzodiazepines

What is somnolence, dizziness, and ataxia?

200

Pharmacies must be certified and the patient must be enrolled in a REMS program to receive this medication:

What is Clozapine?

200

Natural product that may be beneficial in treating depression, but is a strong CYP3A4 inducer with many significant drug interactions:

What is St. John's Wort?

200

FDA-approved not only for depression, but also for peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain:

What is duloxetine?

300

Boxed warning for all antidepressants:

What is the possible increased risk of suicidal thoughts or actions?
300

Safe for use in elderly patients with liver impairment

What are Lorazepam, Oxazepam, and Temazepam (LOT)?

300

Common side effects from second-generation antipsychotics:

What is metabolic syndrome (increased blood glucose, increased weight, and increased lipids)?

300

The therapeutic range for lithium:

What is 0.6 - 1.2 mEq/L (trough level)?

300

True/False: Paroxetine is one of the first-line agents for depression in pregnancy:

What is false?

400

Second-line drug treatment that takes 2-4 weeks for effect

What is buspirone?

400

Boxed warning for benzodiazapines:

What is use with opioids can result in sedation, respiratory depression, coma, and death?

400

A first-generation antipsychotic that is high-potency and is in the butyrophenone class:

What is haloperidol?

400

Key drugs that cause or worsen depression:

What are isotretinoin, clonidine, beta-blockers, systemic steroids, SSRIs, SNRIs, etc.?

400

Antipsychotic preferred in Parkinson's disease:

What is quetiapine?

500

Select drugs that cause anxiety:

What are Decongestants, Illicit drugs (LSD, cocaine, methamphetamine), Stimulants, Steroids, Antipsychotics?

500

Clonazepam and diazepam's contraindications:

What is severe liver impairment?

500

Baseline ANC must be ______ before initiating clozapine:

What is ≥ 1500/mm^3

500

______ requires slow titration due to the risk of a severe rash:

What is lamotrigene?

500

Used commonly in oncology and skilled nursing facilities to help with sleep, and to increase appetite:

What is mirtazapine?

600

Hypertensive crisis or serotonin syndrome can occur when MAO inhibitors are taken with these agents/foods:

What are SSRIs, SNRIs, and tyramine rich foods?

600

True or false: benzodiazepines should be used as monotherapy in the treatment of anxiety:

What is false? 

600

Monitoring parameters for lithium:

What is serum lithium levels, renal function, and thyroid function (TSH, FT4)?

600

Most activating SSRI:

What is fluoxetine?

600

Brand name of olanzapine + fluoxetine?

What is Symbyax?
700

The washout period needed if changing between SNRIs and MAO inhibitors:

What is 14 days is recommended?

700

______ is contraindicated with strong CYP3A4 inhibitors such as ketoconazole and itraconazole:

What is alprazolam?

700

Can be an irreversible side effect of antipsychotics:

What is tardive dyskinesia?

700

When treating bipolar disease in pregnancy, avoid these agents:

What are valproate, carbamazepine, and lithium?

700

True/False: In the treatment of bipolar disorder, antidepressants can induce or exacerbate a manic episode when used as monotherpy:

What is true, they should only be used in combination with a mood stabilizer?

800

Natural products that increase the bleeding risk when paired with SSRIs:

What is ginkgo, garlic, ginsing, glucosamine, ginger, and fish oils?

800

The antidote for benzodiazapine overdose

What is flumazenil?

800

Antipsychotics to avoid in patients with cardiac risk/QT risk:

What is ziprasidone, haloperidol, thioridazine, or chlorpromazine? 

800

Severe side effect of trazodone in men:

What is priapism?

800

Not FDA approved for anxiety, but has shown benefit in patients with anxiety and neuropathic pain

What is pregabalin and gabapentin?

900

SSRI that is preferred in patients with cardiac risk:

What is sertraline?

900

Commonly used for alcohol withdrawal syndrome:

What is lorazepam, diazepam, and chlordiazepoxide?

900

The boxed warning for thioridazine:

What is QT prolongation?

900

These agents are approved as augmentation therapy with antidepressants for treatment-resistant depression:

What is buspirone, aripiprazole, olanzapine + fluoxetine, quetiapine ER, and brexpiprazole?

900

Three MAO inhibitors:

What is Isocarboxazid (Marplan), Phenelzine (Nardil), and Tranylcypromine (Parnate)?

1000

Max daily dose of citalopram in elderly (> 60 years):

What is 20 mg/day due to increased risk of QT prolongation?

1000

Brand name of clorazepate:

What is Tranxene-T?

1000

The first medication approved for treatment of tardive dyskinesia:

What is valbenazine (Ingrezza)?

1000

______ has the most favorable safety profile in pregnancy when treating bipolar disease, but use is limited due to being only FDA approved for bipolar depression 

What is lurasidone (Latuda)?

1000

Key drugs contraindicated with MAO inhibitors that increase serotonin:

What is linezolid, lithium, tramadol, opioids, St. John's wort, SSRIs, SNRIs, mirtazapine, trazodone, triptans, buspirone, and dextromethorphan?