IM Jeopardy

Zoonotic Disease

100

Bats

Rabies

200

Feral cats (2) 

Toxoplasmosis, cat-scratch disease (Bartonella henselae)

300

Prairie dogs

Bubonic plague, Yersinia pestis

400

Chimpanzees (2)

HIV, monkeypox

500

Reduviid bugs

Chagas disease

Overdoses and their reversal

100

Malignant Hyperthermia

Dantrolene

200

highly lipophilic drug overdose induced cardiac arrest (LAST)

lipid 20% emulsion

300

Valproate‐induced hyperammonemia or hepatic dysfunction

L-carnitine

400

extravasation of vasopressors

phentolamine

500

general poisoning/overdose

Charcoal

New Abx against MDRO

100

This cephalosporin works as a Siderophore, entering through iron transport systems and works against CR-E (Carbapenem-resistant Enterobacterales), CR-PA (Carbapenem-resistant Pseudomonas aeruginosa), and CR-AB (Carbapenem-resistant Acinetobacter baumannii)  

Cefiderocol

200

This Fluoroquinolone work by Inhibition of bacterial DNA topoisomerase IV and DNA gyrase (topoisomerase II), disrupting DNA replication and works against MRSA

Delafloxacin, Lascufloxacin, Alalevonadifloxacin

300

This β-Lactam (Carbapenem)/ β-lactamase inhibitor combination works by Inhibition of cell wall synthesis and works against CR-E

Meropenem/Vaborbactam, Imipenem/Relebactam, Meropenem/Nacubactam

400

With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat which two hard-to-treat infections

drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA)

500

A newly discovered, potent broad-spectrum lasso peptide antibiotic that targets the bacterial ribosome, offering a potential new treatment against drug-resistant bacteria like Acinetobacter baumannii. Discovered in soil-dwelling Paenibacillus bacteria, this compound holds promise for combating multidrug-resistant infections, though it is currently in the preclinical development stage

Lariocidin

Name that Wave

100

EKG 100

Massive pericardial effusion produces a characteristic ECG triad of:

• Low QRS voltage
• Tachycardia
• Electrical alternans

200

EKG 200

Atrial tachycardia 

• Atrial rate > 100 bpm
• Abnormal P wave morphology and axis (e.g. inverted in inferior leads) due to ectopic origin
• Unifocal, identical P waves
• Isoelectric baseline (unlike atrial flutter)
• Normal QRS morphology (unless pre-existing bundle branch block, accessory pathway, or rate-related aberrant conduction)

300

EKG 300

Dextrocardia

• Right axis deviation
• Positive QRS complexes (with upright P and T waves) in aVR
• Lead I: inversion of all complexes, aka ‘global negativity’ (inverted P wave, negative QRS, inverted T wave)
• Absent R-wave progression in the chest leads (dominant S waves throughout)

400

EKG 400

Wellens Syndrome is a clinical syndrome characterised by biphasic or deeply inverted T waves in V2-3, plus a history of recent chest pain now resolved. It is highly specific for critical stenosis of the left anterior descending artery (LAD)

500

EKG 500

Yamaguchi Syndrome: Non-obstructive variant of Hypertrophic Cardiomyopathy (HCM) 

• The classic ECG finding in apical HCM is giant T-wave inversion in the precordial leads. Inverted T waves are also commonly observed in the inferior and lateral leads
• Localized hypertrophy of LV apex, causing an “ace of spades” configuration of the LV cavity on ventriculography

Interesting facts

100

Henbane wreaths were said to be worn when people crossed the river of styx into the other world after death. This drug has been derived from henbane and is use in hospice care 

Hyoscyamine

200

If you take all your blood vessels out and line them up, they'd be long enough to stretch how many times around earth?

2.5x

300

1 g of this drug can  make a flower stand straight for 1 week longer than normal 

Sildenafil 

400

Found in nature, this was used as primitive bandages to stop bleeding and protect wounds, dating back to ancient Greece and Rome, due to their strength and potential antiseptic properties. They also contain Vitamin K 

Spider Webs

500

Beside a fingerprint, what other part of the body is unique to each person

Tongue Print