The Basics
First line of defense
Second Line of Defense
Third Line of Defense
Memory and disorders
200

This structure sends out lymphocytes that help fight infection.

A. Stomach

B. Lungs

C. Lymph nodes

D. Kidneys

What is C, Lymph nodes


200

Give the definition of the innate defense system

What is The innate system is the nonspecific defense system we are all born with that is activated when any foreign invaders try to enter the body

200

Describe the second line of defense

What is 

the body’s innate, non-specific internal immune system

or 

The second line is the innate immune response: fast and non-specific, acting within minutes or hours.

200

Describe the Third Line of defense

What is 

The adaptive immune response is highly specific to individual pathogens and creates immunological memory.

200

What is the role of memory B cells and memory T cells in adaptive immunity?


What is 

Memory B cells quickly produce antibodies against familiar antigens; memory T cells help destroy infected cells and coordinate the immune response.

400

Name the two main defense mechanisms that make up the immune system.


What is Innate and Adaptive

400

 The innate system is the nonspecific defense system we are all born with.

What is 

The innate system responds immediately to protect our body from foreign substances.

400

What is the main role of pattern recognition receptors (PRRs)?


What is 

detect common features of pathogens

400

B cells differentiate into plasma cells, which produce these molecules that bind to antigens:

A. Interferons

B. Antibodies (immunoglobulins)

C. Perforin

D. Pattern recognition receptors

What is 

B, Antibodies 


400

How do vaccines help prepare the immune system against future infections?

What is 

Vaccines create immune memory without causing severe disease, allowing a rapid secondary response if the real pathogen enters later.

600

Which cells are a type of white blood cell that travel through blood and lymph vessels to fight infection?

A. Red blood cells

B. Platelets

C. Lymphocytes

D. Stem cells

What is C

600

This enzyme found in saliva and tears destroys bacteria.

A. Amylase

B. Lysozyme D

C. Pepsin

D. Insulin


What is B, Lysozyme D

600

What is most likely to occur when pathogens successfully penetrate the body's physical and chemical barriers?


What is

The bodies innate response is activated, the second line of defense. 

600

Helper T cells (CD4+) primarily do which of the following?

A. Directly kill infected cells

B. Produce antibodies

C. Activate B cells and coordinate the immune response

D. Release lysozyme D

What is C


600

What is immune amnesia, and which virus is associated with it?

What is 

 Immune amnesia is when viruses (like measles) destroy immune memory cells, making a person vulnerable to previously-fought infections.

800

What type of threats does the immune system protect our body against. 

What is infection, cancer, and other conditions caused by foreign substances.

800

Sticky mucus in the digestive and respiratory passageways is an example of which type of barrier?

A. Adaptive barrier

B. Chemical barrier only

C. Physical barrier that traps microorganisms

D. Third line of defense

What is C

800

These specialized white blood cells patrol the body and destroy pathogens by engulfing them.

A. B cells

B. T cells

C. Phagocytes / Macrophages

D. Plasma cells

What is 

C, Phagocytes

800

Cytotoxic T cells (CD8+) kill infected cells by releasing these two things:

A. Antibodies and interferons

B. Perforin and granzymes

C. Lysozyme and mucus

D. PRRs and NK cells

What is B


800

How does trained immunity in innate immune cells differ from adaptive immune memory?

What is 

Trained immunity in innate cells (macrophages, monocytes) responds more strongly even to different future threats; adaptive memory is specific to a particular antigen.

1000

Name two organs involved in activating lymphocytes 

What is lymph nodes, spleen, tonsils, appendix 

1000

The stomach mucosa secretes gastric juice to kill pathogens. What does this juice contain?

A. Lysozyme and mucus

B. Hydrochloric acid and protein-digesting enzymes

C. Antibodies and interferons

D. Lymphocytes and NK cells

What is B

1000

Natural Killer (NK) cells target which types of cells?

What is 

NK cells identify and destroy infected host cells, such as virus-infected or cancerous cells.

1000

In the COVID-19 example, B cells produced antibodies targeting which part of the virus?

A. The viral RNA

B. The spike proteins

C. The cell membrane

D. The mitochondria

What is B

1000

Multiple Sclerosis is an autoimmune disease where the immune system attacks:

A. Red blood cells and platelets

B. The myelin covering of nerve fibers in the brain and spinal cord

C. The lymph nodes directly

D. Stomach lining and digestive enzymes

What is 

B