AIDS and Such
This type of hypersensitivity is also referred to as DELAYED
What is Type IV hypersensitivity
What type of vaccine uses chemically inactivated toxins to stimulate antibody responses?
Double Points: Name the one given
Toxoid
DTP (Diphtheria and tetanus toxoids with heat-killed pertussis bacteria)
What is central tolerance?
Deletion of self-reactive B/T cells during development.
In HIV attachment this glycoprotein attaches to CD4 and CCR5 or CXCR4
gp120
ALSO REMEMBER: gp41 is for fusion of viral and T cell membranes
What transplant disease is caused by donor-derived T cells and B cells attacking the recipient tissues?
GVHD
Graft Versus Host Disease
What are the three immunoediting phases? Must be listed in order for points.
phase I: elimination
phase II: equilibrium
phase III: escape
What is known as the acute worsening of inflammatory symptoms of autoimmune disease or infections related to the recovery of immune responses to pre-existing opportunistic pathogens?
Immune Reconstitution and Inflammatory Syndrome (IRIS)
Which adjuvant creates an antigen depot at the site of infection that results in slow release of antigen?
Is a pro-Th2 immunity modulator
Aluminum Salts (Alum)
What is AIRE deficiency responsible for?
Autoimmune attack on endocrine glands
(AIRE = AutoImmune Regulator -> promotes expression of tissue-specific antigen cells in thymus epithelial cells.
Name the 3 HIV Diagnostic methods. Names of the tests are acceptable
PCR (Nucleic acid detection)
ELISA (Anti-HIV antibody detection)
Western Blot (Anti-HIV antibody detection and HIV protein detection)
Give one of the three examples of maintenance therapy in transplant rejection?
Glucocortioids
Calcinuerin Inhibitors
Anti-Proliferating Agents
A cell lacking an MHC class I is recognized as a tumor and goes through apoptosis due to perforin and granzymes. What type of cell recognition is this?
NK cell recognition
Name the 5 Medication classes that are indicated for Asthma. Must have AT LEAST 4 for points
Beta 2 agonists
Leukotriene modifiers
Corticosteroids
Anticholinergics
Mast Cell Suppressors
If a mother who is Rh negative and an Rh positive baby, what could happen to her next baby if the new baby is Rh positive
The anti-Rh antibodies will cross the placenta and damage fetal red blood cells
Which antigen presenting gene is linked to PAIR diseases. Most people with this do not have disease.
HLA-B27