TODDLING T CELLS
A T cell is born in this state, expressing neither CD4 nor CD8.
Double negative.
This form of secondary lymphoid tissue found in the mucosa contains mostly B cells.
Isolated lymphoid follicle.
The main recombination event of an early pro-B cell.
D-J.
The type of memory T cell that stays in the tissue where an infection took place.
Resident memory.
These thymocytes must now undergo positive selection.
Mature double positive.
This type of T cell never needs its receptor checked during maturation.
γδ T cell.
These cells in the mucosa do not produce cytokines, a deviation from their normal function.
Macrophages.
The genes necessary for the formation of the BCR (and the TCR too).
RAG genes.
This type of vaccine consists of a carbohydrate antigen complexed with a toxoid.
Conjugate vaccine.
A place a B cell may form a germinal center near the intestines.
Mesenteric lymph node.
The outcome of a T cell binding to MHC in the absence of B7 costimulation is a form of this two word phrase.
Peripheral tolerance.
SCFA is short for this; they may have an anti-inflammatory or immuno-regulatory effect.
Short chain fatty acid.
The two segments making up the surrogate light chain.
VpreB and λ5.
This scientist pioneered the process of attenuation, with help from experimental rabbits.
Louis Pasteur.
"M" is for Moderna, one of the first companies to commercially manufacture this type of vaccine, another "M".
mRNA.
This part of the pre-TCR associates with the CD3 complex and the ζ chain.
Superdimer.
This specific type of antibody found in the mucosa has an abnormally long hinge region, allowing it to better bind its epitope.
IgA1
The greek letter denoting the heavy chain.
μ.
The receptor expressed by Naive B cells, but not memory B cells, that allows for activation to be inhibited if high affinity IgG is present.
FcγRIIB1.
For an autoreactive B cell, receptor editing seems to be reserved for binding to this three word type of antigen.
Multivalent self antigen.
The cytokine and transcription factor required for T cell development.
IL-7 and Notch1.
This two word phrase is the result of CD103 dendritic cells responding to food antigens in a way that causes CD4 cells to differentiate into TREG cells.
Oral tolerance.
The two transcription factors required throughout the entire process of B cell development.
E2A and EBF.
Besides the variola virus, the only other disease that has been completely eradicated.
Rinderpest.
This scientist was responsible for developing over 40 vaccines including those for two other "M's", Measles and Mumps.
Maurice Hilleman.