T cells
Lymphoid organ where T cells mature
What is the Thymus
Name 3 cells that can present antigen
What are: B cells, dendritic cells, macrophages
Define Cytokine
What are soluble chemical mediators of the immune system
Name the 3 complement pathways
What are the Classical, Alternate, Mannose Binding Lectin pathways
This is the end stage B cell and produces gobs of antibody
What is plasma cells
Name the 3 types of T lymphocytes
What are the:
T helper
Cytotoxic
Regulator
Cell capable of target cell destruction without prior exposure
What is a Natural Killer cell
Name 3 types of cytokines
Chemokine (lymphokine)
Interleukin
Interferon
Tumor Necrosis Factor
List what activates each of the 3 pathways
Classical = Ag/Aby Complex
Alternate = Foreign surface + C3b
Mannose Binding Lectin = Mannose groups on microbe surface
Sight of B cell maturation
What is bone marrow
List the CD markers on both mature T Helper cells and Cytotoxic T cells
What is CD2, CD3 and CD4 on T helper
What is CD2, CD3 and CD8 on Cytotoxic
Particles recognized by phagocytes since these cells cannot identify individual antigen
What are Pathogen Associated Molecular Particles (PAMPs)
Which interleukin in Innate immunity initiates an acute phase response
IL-1
Portions of complement are considered the Membrane Attack Complex
What is C5bC6C7C8C9
B cells cells require APC's for an immune response (T/F)
Cytotoxic T cells are associated with which MHC class
What is MHC 1
Antigen presentation to this cell ultimately destroys the APC
What is a Cytotoxic T cell
Which interleukin in Adaptive Immunity downregulates the immune response
IL-10
Name the substance that encourages degranulation of basophils
What is an anaphyltoxin
What is adaptive
T helper cells are subdivided by cytokine produced. Name two.
Th1
Th2
Th17
What is the immune response when an APC interacts with a T Helper cell
What is cytokine production, mobilizes B cells to produce anitbody
Cytokines are found in both the Innate and Adaptive Immune system (T/F)
What is true
List 3 regulators of complement
C1INH
Factor I
Factor H
CR1
Decay Accelerating Factor
C4BP
Memory B cells participate in the secondary immune response. This response is also called _______.