Drug Class
The drugs Prednisolone, hydrocortisone, and dexamethasone belong to what drug class
What are Glucocorticoids?
These drugs work by inhibiting NfKB, downregulating several immune mediators, leading to suppression of B and T cells
What are Glucocorticoids
What side effect is associated with all monoclonal antibidies that can relate to a decrease in their effectiveness
What is the formation of anti drug antibodies
What are Glucocorticoids
This movie is the first in a trilogy released in 2001, based off a series of books written by someone known as the "father of modern fantasy"
What is the Lord of the Rings: the Fellowship of the Ring?
Muronomab and Daclizumab both are considered what type of drug
What are monoclonal antibodies?
This drug suppresses the immune system by binding cyclophilin, leading to calcineurin inhibition and ultimately Il-2 downregulation.
What is Cyclosporine?
This immunosuppressant is one drug famously known to cause SIADH and hemorrhagic cystitis?
What is Cyclophosphamide?
Because this monoclonal antibody medication is made from mouse proteins, it can cause a hypersensitivity reaction, being its main contraindication
What is Muronomab?
This movie, widely considered one of the greatest of all time and continuously referenced in mainstream media, contains this famous quote: "Leave the gun. Take the cannoli."
What is The Godfather pt1.
Sirolimus is the most known drug of this drug class
What are mTOR inhibitors?
Daclizumab and Basilixumab bind the IL-2 receptors, preventing IL-2 from signalling activation of what kind of cell?
What are T-cells?
Excess use of this drug has been associated with Cushing syndrome.
What are Glucocorticoids?
Azathioprine should not be given with this drug due to potential of profound myelosuppression from blocking Xanthine oxidase, can be lethal in select genetic polymorphism
What is Allopurinol
This movie is a modern mafia movie, set in Boston, following a cat and mouse chase between a police detective in the mob, and a member of the mob infiltrating the police.
What is The Departed?
This drugs is considered a Calcineurin inhibitor
What is Cyclosporine
What 3 drugs work in some way to inhibit purine synthesis
What is Azathioprine, Methotexate, and Mycophenylate Mofentil
Muronumab can have a serious side effect where the immune system becomes overactivated and releases compounds that systematically destroy your organs. What is this called?
What is cytokine release syndrome/cytokine storm?
This drug is heavily contraindicated in renal impairment due to its ability to cause renal failure, especially in the presence of CYP450 inhibitors
What is Cyclosporine?
This movie, set in LA during the 1930's, stars Jack Nicholson's detective character, who starts off as a PI for an lover's affair, which leads him down a conspiracy on land, money, and corruption, involving some of the city's biggest names.
What is Chinatown?
This drug is considered an alkylating agent, and is a well known immunosuppressant
What is Cyclophosphamide
Muronumab works as an antibody to CD3, a component of T cells that is responsible for what?
What is T-Cell Activation?
What drug can cause an increase of risk of developing a CMV infection
What is Mycophenylate Mofentil
This drug is absolutely contraindicated in pregnancy due to causing spontaneous abortion from its effects on purine synthesis using inosine monophosphate dehydrogenase
What is Mycophenylate Mofentil?
This movie follows a Clint Eastwood's character, an old former outlaw, called up one more time for a bounty to seek justice for the disfigurement of a local prostitute by the sheriff's posse. This film reimagines the wild west in a new light from how it has traditionally been presented.
What is Unforgiven?