Side Effects or Monitoring
What are two adverse effects associated with vancomycin?
Nephrotoxicity and Ototoxicity
Which class of antibiotics is most associated with QT interval prolongation?
Macrolides
What is the preferred antibiotic for MSSA?
Cefazolin
In a patient with a beta-lactam allergy, which drug classes should be avoided?
Penicillin, cephalosporins, carbapenems
True or False: Doxycycline requires light protection during administration
True
Which antibiotic should not be given to children <8 years old due to teeth discoloration?
Tetracyclines
Which medication carries a black box warning for Clostridioides difficile infection?
Clindamycin
Which bacteria are primarily covered by vancomycin?
Gram-positive bacteria
What is the typical dosing regimen for nitrofurantoin for UTIs?
BID
A patient develops pneumonia 56 hours after being admitted to the hospital. What type of pneumonia is this?
Why is alcohol contraindicated in patients taking metronidazole?
Can cause a disulfiram-like reaction
Which drug class has a black box warning for tendon rupture?
Fluoroquinolones
What is the most common bacterial pathogen causing a UTI?
E Coli
Which agent is used to eliminate nasal MRSA colonization?
Mupirocin nasal ointment
True or False: You can refrigerate acyclovir
False
What do you monitor in patients on daptomycin and why?
Creatine Phosphokinase (CPK) - Rhabdomyolysis
What is the BBW for isoniazid?
Severe hepatitis (hepatotoxicity)
Which fluoroquinolones are considered “respiratory”?
Ciprofloxacin, Levofloxacin, Gemifloxacin
What antibiotic is used for Clostridioides difficile infection?
Oral vancomycin
How is Penicillin G Benzathine administered?
Intramuscularly
What is the most common hypersensitivity reaction associated with vancomycin?
Red Man Syndrome
In which patient population should itraconazole be avoided?
Congestive Heart Failure
Which classes of antibiotics provide coverage against atypical bacteria?
Macrolides, tetracyclines, fluoroquinolones
Which medication is avoided in the treatment of pneumonia because it becomes inactivated by pulmonary surfactant?
Daptomycin
What is the SMX:TMP ratio?
5:1