Inflammation and Immune Response

Inflammation

100

Phases of inflammation

1. Acute inflammation healing

2. Chronic inflammation healing

3. Granuloma formation

4. Healing

200

Causes of dysfunctional wound healing 

hypoxemia, nutritional deficiencies, drug use

300

Chronic inflammatory responses

neutrophils degranulated and die, lymphocytes infiltrate, fibroblasts secrete collagen (protein), pus is produced and self digested, a granuloma may form, tissue repair, scar formation

400

System that is comprised of 11 proteins that assist in destroying or limiting the damage of an invading organism

Complement System

500

System that acts slower than than histamine and is triggered by factors associated with the coagulation cascade

Kinin System

Immune Response

100

Describe IgM

First antibody produced in the primary immune response, largest immunoglobulin

200

Forms of immunity

Natural, acquired, primary, secondary

300

Functions of antibodies

neutralize bacterial toxins, opsonize bacteria, neutralize viruses, activate inflammatory process

400

Cell-mediated immune response results in..

Memory, delayed hypersensitivity, cytotoxicity, control

500

Direct effects of antibodies

Agglutination, precipitation, neutralization

Physiology

100

Self defense mechanisms (3)

Anatomic barriers

inflammatory response

immune response

200

Examples of anatomic barriers

External and non-specific

Epithelium, sebaceous glands, sweat, tears, saliva

300

Characteristics of the inflammatory response

Immediate action against invasion, non-specific action of isolation/destruction/elimination, involves multiple plasma protein systems

400

Characteristics of the immune response 

Develops slowly, may require sensitization, specific (targeted to known pathologic invaders), lymphocytes are usually the sole attacker

500

Infectious agents (5)

bacteria, viruses, fungi, parasites, prions

Surprise Me

100

how does aging effect the immune response

Deteriorates with age

200

Stages of stress

Alarm, resistance, exhaustion

300

Types of Hypersensitivity

allergy( environmental antigens)

Autoimmunity(self antigens)

isoimmunity(other person's antigen)

400

What hormone is the "stress" hormone

Cortisol

500

Functions of catecholamines

triggers "fight or flight" mechanism

should be 500 a pop

100

Blood types and compatibility 

Too much to type.. soooo

200

Acquired Immune Deficiencies 

Nutritional, latrogenic, deficiencies caused by trauma, Acquired immunodeficiency syndrome

300

Describe Immune Complex Mediated (type 3)

Formation of antigen-antibody complexes when antibodies in blood or in body secretions meet and bind to a specific antigen

the affected organ has very little connection with where or how the antigen or the immune complex originated 

400

Clinical indications of a hypersensitivity reaction (Type 1)

Hives, breathing difficulty, increase heart rate and blood pressure, nausea, vomiting, diarrhea, headache, dizziness, tearing, convulsions

500

Processes for immune response

Antigen processing, antigen presentation, antigen recognition