MALDI-TOF
This is the meaning of the MALDI acronym
What is Matrix-Assisted Laser Desorption/Ionization?
This is the meaning of the FT-ICR acronym
What is Fourier Transform Ion Cyclotron Resonance?
The acronym MRM stands for this.
What is multiple reaction monitoring?
In an Orbitrap, ions move back and forth around this part in the center.
What is the central electrode?
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Is it, and how do we know?
In MALDI, this is the substance that absorbs laser energy and transfers it to the analyte for ionization.
What is the matrix?
FT-ICR provides the best results for this analytical metric that closely relates to accuracy and sensitivity
What is resolution?
TQMS is often paired with these separation techniques.
What are gas chromatography and liquid chromatography?
In an Orbitrap, the detected signal from the ion oscillations is converted into a mass spectrum using this mathematical transformation.
What is a Fourier transform?
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MALDI-TOF is commonly used to identify this type of biological molecule in proteomics.
What are proteins (or peptides)?
Unlike traditional mass spectrometers, the ICR frequency (signal) of an analyte at a given m/z on FT-ICR has no direct relation with this measurement and is instead determined solely by m/z ratio and magnet strength
What is analyte velocity?
The process in Q2 by which ions collide with gas molecules and fragment into smaller ions is called this.
What is collision induced dissociation (CID)?
This term describes the Orbitrap’s ability to distinguish ions with very similar m/z values, such as 100.000 and 100.005.
What is mass resolution?
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This modification to TOF systems improves resolution by compensating for differences in ion kinetic energy.
What is a reflectron?
The number of unique sets of electrodes that typically make up the inside of the ICR chamber of this instrument
What is 3?
In a triple quadrupole MS, Q3 typically performs this function.
What is mass analysis of the fragment ions (product ion scanning)?
The term “transient” in Orbitrap data refers to this type of signal recorded before being converted to a frequency domain spectrum.
What is the time-domain signal; image current transient?
The name of the equation that relates variables such as scan rate, current, electroactive surface area, and more on an electrode
What is the Randles-Sevcik Equation?
The time-of-flight of an ion is proportional to this mathematical expression involving its mass-to-charge ratio.
What is the square root of m/z
Fourier Transform works by converting this representation of an analyte's signal into a frequency domain
What is a time-domain?
When both Q1 and Q3 scan synchronously with a fixed m/z offset, it’s known as this type of scan.
What is a neutral loss scan?
Unlike time-of-flight or quadrupole instruments, the Orbitrap’s accuracy is limited primarily by this type of noise—arising from the random arrival of ions that cannot be corrected due to quantum principles.
What is shot noise?
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What are Concordia College (Kira) U of Wisconsin (Molly)?