SKIN LAYERS
CELLS
SLIDES
STRUCTURES OF SKIN
100

What is the deepest layer of the epidermis, responsible for cell renewal?

What is the stratum basale

100

Fully differentiated keratinocytes contain ___% of intermediate filaments.

85

100

1

 1

100

Which nerve ending has pressure receptors?

Pacinian corpuscles

200

Which layer of the epidermis is also known as the prickle cell layer due to desmosome connections?

What is the stratum spinosum

200

Melanin is produced by the oxidation of …………

tyrosine.

200

2

2

200

What are the 4 regions of the hair follicles?

Infundibulum, isthmus, follicular bulge, inferior segments


300

This layer is only present in thick skin and appears as a thin, transparent band under the microscope.

What is the stratum lucidum?

300

hat is the function of filaggrin?

used as clinical marker for the final stage of apoptosis

300

3

3

300

What is the name of the hormone that activates the sebaceous gland?

Androgen

400

Which layer of the dermis contains type I collagen, forms Langer lines, and provides tensile strength to the skin?

What is the reticular layer?

400

Name the lipid molecule which is consisted in epidermal water barrier and triggers apoptosis.

ceramides

400

4

4

400

What are the 3 layers of the internal root sheath? what type of epithelial cells are there?


  • Henle’s layer-single cuboidal cells(external root sheath)
  • Huxley layer-single/double flattened cells
  • Internal root sheath cuticle-squamous cells
500

The process by which keratinocytes undergo a specialized form of apoptosis, losing their nucleus while retaining keratin, is known as what?

What is terminal differentiation?

500

For staining langerhans cells, besides gold chloride impregnation what do we use?

A: Antibody against CD1a molecules

500

5

5

500

What makes the hair shaft rigid?

high sulfur KAPs