Pembrolizumab and ipilimumab are examples of this therapeutic class
What are checkpoint inhibitors
Name two of the classic nephrotic diseases?
For for the first time in several months, this person was seen publicly alongside Jill Biden on Mother's Day
Olena Zelenska (first lady of Ukraine)
Interventional cardiologists may sometimes infuse abciximab, tirofiban, or eptifibatide alongside ASA peri-PCI in patients who might not tolerate P2Y12 inhibitors or high risk of thrombus. What class do these drugs belong to?
Glycoprotein (GP) IIB/IIIA inhibitors
Causative agent in 80% of cases of septic arthritis
Staph Aureus
Name this illness script: facial flushing, leathery skin, chronic smoker, and headache
What is SVC syndrome/pancoast tumor
Approximate 5 year survival rate of a patient who begins hemodialysis today (assuming no other competing illnesses) +/- 10%
What is 35%
When Elon Musk first attempted to buy Twitter, board members used this business tactic to ward him off (temporarily)
Poison Pill
What is the first line therapy for fibromyalgia treatment that results in fewer subspecialty referrals
Regular aerobic exercise
Name two of the three most common sites of metastasis in malignant melanoma
What is CNS/Brain, Lung, Liver
Dr. Gladwin will be serving as Dean of this medical school starting August 1
University of Maryland
HOCM, long-QT, WPW, and Brugada syndrome are all predisposing conditions of what?
Sudden cardiac death
A 28-year-old woman seeks preconception counseling. She has a 4-year history of systemic lupus erythematosus (SLE) with manifestations of photosensitive rash, arthritis, and pericarditis; she has been treated with hydroxychloroquine and low-dose prednisone with good control of her symptoms for 18 months. Her SLE labs show ANA (1:1320), positive anti-Ro/SSA antibodies, and negative anti-U1, anti-dsDNA, and anti-Smith antibodies. She is counseled about the increased risk of preeclampsia and preterm delivery. Based on her antibody profile, identify the most important additional risk to the fetus to counsel her about.
Risk of congenital heart block in her baby
When monitoring for TLS, all lab values are expected to be elevated EXCEPT for:
What is calcium
Name the three most helpful labs for working-up hyponatremia
At a near 40-year high, _________ stabilized this week at 8.3%
Inflation
Beta-blockers and ARNI/ARB or ACE/ARB are first-line GDMT for HFrEF (<35%) patients. What two other drugs are part of the HFrEF GDMT algorithm?
Aldosterone antagonists and SGLT2i
Name the four most common seronegative polyarthropathies
Name two cancers for which checkpoint inhibitors (immunotherapy) are now first line treatment
Despite a last-minute plea to “respectfully bow out” of contention for the Rock & Roll Hall of Fame, the country singer __________ was voted in anyway.
Dolly Parton
What HR-lowering drug can be added alongside HFrEF GDMT in patients already on maximally dosed B-blockers
Ivabradine
Most common antibody directed against histidyl–tRNA synthetase
Anti-Jo1