Germ Layers
Primitive Streak
Mesoderm
Folding & Flow
Heart Builders
100

This layer replaces the hypoblast and becomes the lining of internal organs.

What is the endoderm?

100

This structure marks the beginning of gastrulation. 

What is the appearance of the primitive streak?

100

This subdivision of mesoderm specifically contributes to heart development. 

What is the lateral plate mesoderm?

100

Folding transforms the embryo into this structural arrangement.

What is a "tube within a tube"?

100

The first functional organ to develop.

What is the heart?

200

This layer gives rise to muscle, connective tissue, and the cardiovascular system.

What is the mesoderm?

200

Cells enter the embryo through this structure. 

What is the primitive groove?

200

This layer of the lateral plate mesoderm directly forms the heart.

What is the splanchnic mesoderm?

200

This type of folding moves the heart into the thoracic cavity.

What is cranio-caudal folding?

200

This structure forms the initial heart tube.

What is the first heart field?

300

This layer forms both the nervous system and the skin.

What is the ectoderm?

300

This is the expanded cranial end of the primitive streak.

What is the primitive node?
300

Cardiogenic mesoderm originates from this structure before migrating cranially.

What is the primitive streak?

300

This type of folding brings the paired endocardial tubes together, so they can fuse.

What is lateral folding?

300

This heart field contributes to elongation and added complexity

What is the second heart field?

400

All 3 germ layers originate from this structure.

What is the epiblast?

400

This term describes cells moving inward and detaching from the surface.

What is delamination?

400

This crescent shaped structure forms from cardiogenic mesoderm and represents the earliest visible stage of heart development.

What is the cardiac crescent (first heart field)?

400

This structure receives systemic venous blood and serves as the inflow region of the primitive heart tube.

What is the sinus venosus?

400

These paired structures fuse to form the primary heart tube.

What are endocardial tubes?

500

This germ layer is formed last, after cell migration through the primitive streak has ceased.

What is the ectoderm?

500

This cell movement process both narrows and lenghtens the primitive streak during development. 

What is convergent extension?

500

This process brings the right and left cardiogenic regions together at the midline, allowing formation of the primitive heart tube.

What is lateral folding?

500

This is the correct direction of blood flow through the primitive heart tube.

What is: sinus venosus- primitive atrium-primitive ventricle- bulbus cordis- truncus arteriosus?

500

This condition results in mirror-image organ positioning.

What is situs inversus?