Advanced Neuroscience
Modern Research and Policy
Cultural Significance
Psychedelics in Literature and Media
Mystical Experiences
200

This neurotransmitter system, often implicated in so-called 'drugs of abuse,' is NOT significantly impacted by classic psychedelics.

What is dopamine?

200

This U.S. city was the first to decriminalize psilocybin in 2019.

What is Denver?

200

This phrase describes the Western adaptation of indigenous practices, often criticized for commodification and loss of original cultural context.

What is cultural appropriation?

200

This book by Aldous Huxley describes his mescaline experiences.

What is The Doors of Perception?

200

This scale measures the intensity of mystical experiences induced by psychedelics.

What is the Mystical Experiences Questionnaire?

400

This brain imaging method shows how psychedelics alter functional connectivity in the brain.

What is fMRI?

400

In 2020, this state became the first to legalize psilocybin therapy.

What is Oregon?
400

The Native American Church uses this legal exemption to incorporate a psychedelic substance in its spiritual practices.

What is the Religious Freedom Restoration Act?

400

This Hunter S. Thompson novel portrays a drug-fueled journey through Las Vegas?

What is Fear and Loathing in Las Vegas?

400

Psychedelics often lead to this feeling of profound connection to the universe.

What is 'unity' or 'oneness?'

600

This phenomenon describes the breakdown of ordinary brain connectivity, leading to a state of free association.

What is ego dissolution?

600

In 2018, this FDA designation accelerated research into psilocybin therapy.

What is 'breakthrough' therapy?

600

This indigenous group of northern Mexico uses peyote in elaborate ceremonies that include pilgrimages and offerings.

Who are the Huichol?

600

This 2009 film by Gaspar NoƩ uses visual effects inspired by psychedelics.

What is Enter the Void?

600

A 2006 Johns Hopkins study replicated this experiment showing that psilocybin could induce mystical experiences in healthy volunteers.

What is the Good Friday Experiment?

800

This neurotransmitter system is primarily responsible for the effects of ketamine.

What is glutamate?

800

A 2021 paper describing a 'self-blinding' experiment explored this type of psychedelic use.

What is microdosing?

800

The Santo Daime religion integrates ayahuasca use into its ceremonies, combining it with elements of this religious tradition.

What is Christianity?

800

This counterculture novelist's works, such as One Flew Over the Cuckoo's Nest, was influenced by his participation in the CIA's MK-ULTRA experiments.

Who is Ken Kesey?

800

This is the term for experiences that are deeply meaningful and transformative but defy linguistic description.

What are 'ineffable' experiences?

1000

The claustrum, impacted by psychedelics, is believed to play a role in this integrative brain function.

What is consciousness?

1000

The Controlled Substances Act of 1970 classified psychedelics as Schedule I substances under these criteria.

What is high risk for abuse and no accepted medical use?

1000

This group of surfers and hippies in Southern California were the largest distributors of LSD in the late 1960s/early 70s

What is The Brotherhood of Eternal Love?

1000

in 1999, This creative duo attended the Oscars ceremony wearing dresses while high on LSD.

Who are South Park creators Trey Parker and Matt Stone?

1000

This philosophical concept, often linked to mystical experiences, suggests that reality is interconnected and non-dualistic.

What is monism?